Treatment strategies for myeloproliferative neoplasms

被引:0
作者
Heidel, Florian [1 ]
机构
[1] Univ Med Greifswald, Innere Med C Hamatol & Onkol Stammzelltransplanta, Sauerbruchstr, D-17475 Greifswald, Germany
来源
ONKOLOGIE | 2022年 / 28卷 / 08期
关键词
Myeloproliferative neoplasms; risk-adapted therapy; Polycythemia vera; Thrombocythemia; essential; Primary myelofibrosis; Janus kinase inhibitors; INTERNATIONAL PROGNOSTIC SCORE; POLYCYTHEMIA-VERA; MYELOFIBROSIS; RUXOLITINIB; THROMBOSIS; EFFICACY; THERAPY; SAFETY;
D O I
10.1007/s00761-022-01191-y
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Classical chronic BCR::ABL1-negative myeloproliferative neoplasms include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). In recent years, there has been a significant improvement with respect to therapeutic options and strategies that include novel agents. Interferons, Janus kinase (JAK) inhibitors and combination treatment are among the clinical developments. An exact classification, diagnosis and risk stratification are crucial for optimizing the treatment strategy and personalized treatment.
引用
收藏
页码:721 / 730
页数:10
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