Synthesis and characterization of new acyclic nucleosides analogues derived from 2-phenyl quinoline candidates

被引：1

作者：

Khalifa, N. M. ^{[1
,2
]}

Al-Omar, M. A. ^{[1
]}

Amr, A. E. ^{[1
,3
]}

机构：

[1] King Saud Univ, Dept Pharmaceut Chem, Coll Pharm, Riyadh 11451, Saudi Arabia

[2] Natl Res Ctr, Pharmaceut & Drug Ind Div, Dept Therapeut Chem, Cairo 12622, Egypt

[3] Natl Res Ctr, Appl Organ Chem Dept, Cairo 12622, Egypt

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2016年 / 86卷 / 05期

关键词：

beta-glycosides; oxadiazol-2-yl-D-glycosides; quinoline derivatives; AGENTS; DERIVATIVES;

D O I：

10.1134/S1070363216050224

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reaction of 4-substituted quinoline hydrazide with some aldohexoses and aldopentoses gave a series of new N-beta-glycosides. The following cyclization of N-beta-glycosides with acetic anhydride led to O-acetyl-[5-(2-phenylquinolin-4-yl)-1,3,4-oxadiazol-2-yl]-D-glycosides. Structure of the newly synthesized products was elucidated by chemical and spectroscopic methods.

引用

页码：1115 / 1119

页数：5

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