Aging: All in the head?

被引：6

作者：

Bartke, Andrzej ^{[1
]}

机构：

[1] So Illinois Univ, Sch Med, Dept Internal Med, Springfield, IL 62794 USA

[2] So Illinois Univ, Sch Med, Dept Physiol, Springfield, IL 62794 USA

来源：

CELL METABOLISM | 2007年 / 6卷 / 03期

关键词：

D O I：

10.1016/j.cmet.2007.08.007

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Global reduction in insulin signaling has been linked to extended life span in a range of organisms. New work on mice with brain-specific or whole-body reductions in insulin receptor substrate 2 (IRS2) (Taguchi et al., 2007) points to a role for insulin/IGF-1 signaling in the central control of mammalian aging.

引用

页码：153 / 154

页数：2

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