Vaping-associated lung injury

被引:3
作者
Xantus Gabor [1 ]
Kanizsai Peter Laszlo [2 ,3 ]
机构
[1] Cardiff Univ, Cardiff CF10 3AT, Wales
[2] Pecsi Tud Egyet, Klin Kozpont, Surgossegi Orvostani Tanszek, Surgossegi Betegellato Osztaly, Pecs, Hungary
[3] Semmelweis Egyet, Altalanos Orvostud Kar, Aneszteziol & Intenz Terapias Klin, Budapest, Hungary
关键词
vaping-associated lung injury; dyspnoe; cannabinoids;
D O I
10.1556/650.2020.31671
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Over 1000 respiratory cases have been linked to vaping at the Centers for Disease Control and Prevention (Atlanta, GA, USA). So far at least 800 cases were confirmed as vaping-associated lung injuries (VALI) with 18 patients succumbing to the illness. To our present knowledge, vape fluids may contain certain compounds with toxic properties. It is not yet understood though what component or components are responsible for the cluster of cases. However, federal and state investigators are focusing on vape cartridges that likely contained cannabinoids as most patients vaped legal or illegal cannabinoids. Until recently, USA and UK public health authorities have welcomed vaping as a safer alternative to smoking. In countries where cannabis has been legalised, vaporizers became an increasingly popular form of administration, however, no human studies have been performed with vaporized cannabinoid oils, hence the safety of such device is unknown. A 2018 review concluded that although vaping might not necessarily be safe, it is still preferable for both patients and their environment to smoking cannabis. Since 2015, Hungarian, Australian and European scientific bodies have called for ban on the unregulated e-cigarettes, but encouraged future research to understand all aspects of vaping cannabinoids. Should vaping itself prove harmless, it might open new avenues for research and potential administration of medical cannabis, however, the contrary may cause landslide in the tobacco industry.
引用
收藏
页码:413 / 418
页数:6
相关论文
共 24 条
  • [1] Vaping-induced Acute Lung Injury: An Epidemic That Could Have Been Prevented
    Balmes, John R.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 200 (11) : 1342 - 1344
  • [2] Electronic cigarettes: a task force report from the European Respiratory Society
    Bals, Robert
    Boyd, Jeanette
    Esposito, Susanna
    Foronjy, Robert
    Hiemstra, Pieter S.
    Jimenez-Ruiz, Carlos A.
    Katsaounou, Paraskevi
    Lindberg, Anne
    Metz, Carlos
    Schober, Wolfgang
    Spira, Avrum
    Blasi, Francesco
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2019, 53 (02)
  • [3] Electronic Cigarettes A Policy Statement From the American Heart Association
    Bhatnagar, Aruni
    Whitsel, Laurie P.
    Ribisl, Kurt M.
    Bullen, Chris
    Chaloupka, Frank
    Piano, Mariann R.
    Robertson, Rose Marie
    McAuley, Timothy
    Goff, David
    Benowitz, Neal
    [J]. CIRCULATION, 2014, 130 (16) : 1418 - 1436
  • [4] Center for Drug Evaluation and Research, 2019, EXP PROGR SER COND D
  • [5] Centers for Disease Control and Prevention, SYNTH CANN OV HEALTH
  • [6] Centers for Disease Control and Prevention, 2019, SEV PULM DIS ASS US
  • [7] Christiani DC, 2019, NEW ENGL J MED, DOI [10.1056/NEJMMe1912032, DOI 10.1056/NEJMME1912032]
  • [8] Summary of the existing knowledge about electronic cigarettes
    Cselko Zsuzsa
    Penzes Melinda
    [J]. ORVOSI HETILAP, 2016, 157 (25) : 979 - 986
  • [9] Formation of flavorant-propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids
    Erythropel, Hanno C.
    Jabba, Sairam V.
    DeWinter, Tamara M.
    Mendizabal, Melissa
    Anastas, Paul T.
    Jordt, Sven E.
    Zimmerman, Julie B.
    [J]. NICOTINE & TOBACCO RESEARCH, 2019, 21 (09) : 1248 - 1258
  • [10] Gieringer D., 2004, Journal of Cannabis Therapeutics, V4, P7, DOI 10.1300/J175v04n01_02