The association of depressive symptoms with disability among adults in China

被引：17

作者：

Peng, Rui ^{[1
]}

Wang, Yongshi ^{[1
]}

Huang, Yueqin ^{[1
]}

Liu, Zhaorui ^{[1
]}

Xu, Xiangdong ^{[2
]}

Ma, Yanjuan ^{[2
]}

Wang, Limin ^{[3
]}

Zhang, Mei ^{[3
]}

Yan, Yongping ^{[4
]}

Wang, Bo ^{[4
]}

Xiao, Shuiyuan ^{[5
]}

Zhou, Liang ^{[5
]}

Li, Lingjiang ^{[6
]}

Zhang, Yan ^{[6
]}

Ma, Chao ^{[1
]}

Zhang, Tingting ^{[1
]}

Yan, Jie ^{[7
]}

Ding, Hua ^{[7
]}

Yu, Yaqin ^{[8
]}

Kou, Changgui ^{[8
]}

Xu, Xiufeng ^{[9
]}

Lu, Jin ^{[9
]}

Wang, Zhizhong ^{[10
]}

He, Shulan ^{[10
]}

Xu, Yifeng ^{[11
]}

He, Yanling ^{[11
]}

Li, Tao ^{[12
]}

Guo, Wanjun ^{[12
]}

Xu, Guangming ^{[13
]}

Yin, Huifang ^{[13
]}

Du, Xiangdong ^{[14
]}

Wu, Yue ^{[15
]}

Li, Guohua ^{[16
]}

Jia, Fujun ^{[17
]}

Shi, Jianfei ^{[18
]}

Chen, Zheli ^{[19
]}

Zhang, Ning ^{[20
]}

Li, Shengju ^{[21
]}

机构：

[1] Peking Univ, Natl Clin Res Ctr Mental Disorders, Peking Univ Hosp 6,Inst Mental Hlth, NHC Key Lab Mental Hlth Peking Univ, Beijing 100191, Peoples R China

[2] Fourth Peoples Hosp Urumqi, Urumqi 830002, Peoples R China

[3] Chinese Ctr Dis Control & Prevent, Natl Ctr Chron & Noncommunicable Dis Control & Pr, Beijing 100050, Peoples R China

[4] Fourth Mil Med Univ, Dept Epidemiol, Xian 710032, Shaanxi, Peoples R China

[5] Cent South Univ, Sch Publ Hlth, Dept Social Med & Hlth Management, Changsha 410078, Hunan, Peoples R China

[6] Cent South Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha 410011, Hunan, Peoples R China

[7] Peking Univ, Inst Social Sci Survey, Beijing 100871, Peoples R China

[8] Jilin Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Changchun 130021, Jilin, Peoples R China

[9] Kunming Med Univ, Dept Psychiat, Affiliated Hosp 1, Kunming 650032, Yunnan, Peoples R China

[10] Ningxia Med Univ, Sch Publ Hlth & Management, Dept Epidemiol & Hlth Stat, Yinchuan 750004, Ningxia, Peoples R China

[11] Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Sch Med, Shanghai 200030, Peoples R China

[12] Sichuan Univ, Mental Hlth Ctr, West China Hosp, Chengdu 610041, Sichuan, Peoples R China

[13] Tianjin Anding Hosp, Tianjin 300222, Peoples R China

[14] Suzhou Guangji Hosp, Suzhou 215008, Jiangsu, Peoples R China

[15] Nanjing Med Univ, Affiliated Wuxi Mental Hlth Ctr, Wuxi 214151, Jiangsu, Peoples R China

[16] Chifeng Anding Hosp, Chifeng 024000, Inner Mongolia, Peoples R China

[17] Guangdong Gen Hosp, Guangdong Mental Hlth Inst, Guangzhou 510120, Guangdong, Peoples R China

[18] Hangzhou Seventh Peoples Hosp, Dept Psychiat, Hangzhou 310013, Zhejiang, Peoples R China

[19] Third Peoples Hosp Huzhou, Huzhou 313000, Zhejiang, Peoples R China

[20] Nanjing Med Univ, Nanjing Brain Hosp, Nanjing 210029, Jiangsu, Peoples R China

[21] Third Peoples Hosp Qinghai, Xining 810007, Qinghai, Peoples R China

来源：

JOURNAL OF AFFECTIVE DISORDERS | 2022年 / 296卷

基金：

国家重点研发计划;

关键词：

Major depressive disorder; Depressive symptoms; Disability; Community survey; COMMON MENTAL-DISORDERS; HEALTH; COMORBIDITY; PREVALENCE; VERSION;

D O I：

10.1016/j.jad.2021.09.030

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: The symptoms that patients with major depressive disorder (MDD) experience are the dominant contributing factors to its heavy disease burden. This study sought to identify key symptoms leading to disability in patients with MDD. Methods: Subjects consisted of patients who had a 12-month MDD diagnosis based on the China Mental Health Survey (CMHS). World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) was used to assess the degree of disability. The associations between depressive symptoms and disability were analyzed using a linear regression and logistic regression with a complex sampling design. Results: Of the 32,552 community residents, 655 patients were diagnosed with 12-month MDD. The disability rate due to MDD was 1.06% (95% CI: 0.85%-1.28%) among adults in Chinese community and 50.7% (95% CI: 44.3%-57.1%) among MDD patients. Depression was associated with all functional losses measured by the WHODAS. Feelings of worthlessness in life or inappropriate guilt, and psychomotor agitation or retardation were the key symptoms related to disability. Economic status, co-morbidity of physical diseases or anxiety disorders were correlates of disability scores. Limitations: The disability rate might be underestimated due to the exclusion of MDD patients living in hospitals. The effect of treatments on disability was excluded. Conclusions: Psychological symptoms, not somatic symptoms, contribute to disability in MDD patients. Disability worsens when physical diseases or anxiety disorders are present. More attention could be paid to psychological symptoms, physical diseases, and anxiety disorders in MDD patients with disabilities.

引用

页码：189 / 197

页数：9

共 32 条

[1]

Abbafati C, 2020, LANCET, V396, P1204

[2]

[Anonymous], 2010, MANUAL WHO DISABILIT

[3] Disability and common mental disorders: Results from the World Mental Health Survey Initiative Portugal [J].