Practical radical additions under mild conditions using 2,2′-azobis(2,4-dimethyl-4-methoxyvaleronitrile) [V-70] as an initiator

被引：46

作者：

Kita, Y

Gotanda, K

Murata, K

Suemura, M

Sano, A

Yamaguchi, T

Oka, M

Matsugi, M

机构：

[1] Osaka Univ, Grad Sch Pharmaceut Sci, Suita, Osaka 565, Japan

[2] Wake Pure Chem Ind Ltd, Tokyo Res Labs, Kawagoe, Saitama 35011, Japan

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 1998年 / 2卷 / 04期

关键词：

D O I：

10.1021/op970059z

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Radical addition reactions of bromomalononitrile to various alkenes using 2,2'-azobis(2,4-dimethyl-4-methoxyvaleronitrile) (V-70) were examined. The advantages of V-70 which is an effective radical initiator at low temperature in contrast to the other azobis compounds are described, Especially V-70L (the low melting point diastereomer) was found to be the best radical initiator.

引用

页码：250 / 254

页数：5

共 24 条

[1]

BARTELS HM, 1981, LIEBIGS ANN CHEM, P40

[2] FREE-RADICAL ADDITIONS .10. SIMPLE SYNTHESES OF SOME SPIRO[2.4]HEPTANE-4,4,7,7-TETRACARBONITRILES [J].