Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis

被引：246

作者：

Ko, Darae ^{[2
]}

Rahman, Faisal ^{[3
]}

Schnabel, Renate B. ^{[4
,5
]}

Yin, Xiaoyan ^{[6
,7
,8
]}

Benjamin, Emelia J. ^{[6
,7
,9
,10
,11
]}

Christophersen, Ingrid E. ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Cardiovasc Res Ctr, 149 13th St, Charlestown, MA 02129 USA

[2] Boston Univ, Sch Med, Boston Med Ctr, Sect Gen Internal Med, Boston, MA 02215 USA

[3] Boston Univ, Sch Med, Boston Med Ctr, Dept Internal Med, Boston, MA 02215 USA

[4] Univ Heart Ctr Hamburg, Dept Gen & Intervent Cardiol, Martinistr 52, D-20246 Hamburg, Germany

[5] DZHK German Ctr Cardiovasc Res, Partner Site Hamburg Kiel Lubeck, D-13347 Berlin, Germany

[6] Boston Univ, 73 Mt Wayte Ave, Framingham, MA 01702 USA

[7] NHLBI, Framingham Heart Study, 73 Mt Wayte Ave, Framingham, MA 01702 USA

[8] Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02215 USA

[9] Boston Univ, Sch Med, Boston Med Ctr, Sect Cardiovasc Med, 72 East Concord St, Boston, MA 02215 USA

[10] Boston Univ, Sch Med, Boston Med Ctr, Sect Prevent Med, 72 East Concord St, Boston, MA 02215 USA

[11] Boston Univ, Sch Publ Hlth, Dept Epidemiol, 715 Albany St, Boston, MA 02118 USA

来源：

NATURE REVIEWS CARDIOLOGY | 2016年 / 13卷 / 06期

基金：

美国国家卫生研究院; 欧洲研究理事会;

关键词：

GENDER-RELATED DIFFERENCES; CONGESTIVE-HEART-FAILURE; RISK STRATIFICATION SCHEMES; FOLLOW-UP; FAMILIAL AGGREGATION; PHYSICAL-ACTIVITY; SEX-DIFFERENCES; FEMALE SEX; MYOCARDIAL-INFARCTION; ATHEROSCLEROSIS-RISK;

D O I：

10.1038/nrcardio.2016.45

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atrial fibrillation (AF) is the most common sustained arrhythmia in women and men worldwide. During the past century, a range of risk factors has been associated with AF, severe complications from the arrhythmia have been identified, and its prevalence has been increasing steadily. Whereas evidence has accumulated regarding sex-specific differences in coronary heart disease and stroke, the differences between women and men with AF has received less attention. We review the current literature on sex-specific differences in the epidemiology of AF, including incidence, prevalence, risk factors, and genetics, and in the pathophysiology and the clinical presentation and prognosis of patients with this arrhythmia. We highlight current knowledge gaps and areas that warrant future research, which might advance understanding of variation in the risk factors and complications of AF, and ultimately aid more-tailored management of the arrhythmia.

引用

页码：321 / 332

页数：12

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