A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E

被引:67
作者
Assouline, Sarit [1 ]
Culjkovic-Kraljacic, Biljana [2 ,3 ]
Bergeron, Julie [4 ]
Caplan, Stephen [1 ]
Cocolakis, Eftihia [1 ]
Lambert, Caroline [1 ]
Lau, Cara J. [1 ]
Zahreddine, Hiba Ahmad [2 ,3 ]
Miller, Wilson H., Jr. [1 ]
Borden, Katherine L. B. [2 ,3 ]
机构
[1] McGill Univ, Jewish Gen Hosp, Lady Davis Inst, Segal Canc Ctr, Montreal, PQ H3T 1E2, Canada
[2] Univ Montreal, Inst Res Immunol & Canc, Montreal, PQ H3C 3J7, Canada
[3] Univ Montreal, Dept Pathol & Cell Biol, Montreal, PQ H3C 3J7, Canada
[4] Hop Maison Neuve Rosemont, Montreal, PQ H1T 2M4, Canada
关键词
AML; eIF4E; ribavirin; phase I; drug resistance; ONCOGENE EIF4E; INHIBITION; PROMOTES;
D O I
10.3324/haematol.2014.111245
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E7 / E9
页数:3
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