The Reaction of (N-Isocyanimino)triphenylphosphorane with Biacetyl in the Presence of Aromatic Carboxylic Acids: Efficient One-Pot Three-Component Reaction for the Synthesis of 3-(5-Aryl-1,3,4-oxadiazol-2-yl)-3-hydroxybutan-2-one Derivatives

被引：76

作者：

Ramazani, Ali ^{[1
]}

Rouhani, Morteza ^{[1
]}

Rezaei, Aram ^{[1
]}

Shajari, Nahid ^{[1
]}

Souldozi, Ali ^{[2
]}

机构：

[1] Zanjan Univ, Dept Chem, Zanjan, Iran

[2] Islamic Azad Univ, Dept Chem, Urmia Branch, Orumiyeh, Iran

来源：

HELVETICA CHIMICA ACTA | 2011年 / 94卷 / 02期

基金：

美国国家科学基金会;

关键词：

POLYMER-SUPPORTED REAGENTS; X-RAY-STRUCTURE; 1,3,4-OXADIAZOLES;

D O I：

10.1002/hlca.201000219

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reactions of biacetyl (butane-2,3-dione) with (N-isocyanimino)triphenylphosphorane in the presence of aromatic carboxylic acids proceed smoothly at room temperature and under neutral conditions to afford 3-(5-aryl-1,3,4-oxadiazol-2-yl)-3-hydroxybutan-2-one derivatives in high yields.

引用

收藏

页码：282 / 288

页数：7

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