Comparison of Thalamus and Basal Ganglia Signs Between Multiple Sclerosis and Primary Angiitis of the Central Nervous System: An Exploratory Study

被引：0

作者：

Chen, Ying ^{[1
]}

Li, Rui ^{[2
]}

Wu, Aimin ^{[2
]}

Qiu, Wei ^{[2
]}

Hu, Xueqiang ^{[2
]}

Hu, Zhaoqi ^{[3
]}

Yang, Qian ^{[1
]}

Zhou, Zhiming ^{[1
]}

机构：

[1] Yijishan Hosp, Wannan Med Coll, Dept Neurol, Affiliated Hosp 1, Wuhu, Peoples R China

[2] Sun Yat Sen Univ, Dept Neurol, Affiliated Hosp 3, Guangzhou, Peoples R China

[3] Wuhu Tradit Chinese Med Hosp, Dept Orthopaed, Wuhu, Peoples R China

来源：

FRONTIERS IN NEUROLOGY | 2021年 / 12卷

基金：

中国国家自然科学基金;

关键词：

multiple sclerosis; primary angiitis of the central nervous system; basal ganglia; MRI; comparison; DEMYELINATION; HIPPOCAMPAL; IMPAIRMENT; DISABILITY; DIAGNOSIS;

D O I：

10.3389/fneur.2021.513253

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Based on the symptoms, especially those affecting small vessels, it is difficult to distinguish multiple sclerosis (MS) from primary angiitis of the central nervous system (PACNS). Magnetic resonance imaging (MRI) helps understand the characteristics of deep gray matter lesions (DGML) in MS and PACNS. We aimed to compare the MRI characteristics of thalamus and basal ganglia lesions between relapsing-remitting MS and PACNS. In our study, 49 relapsing-remitting MS patients and 16 PACNS with MRI-confirmed thalamus or basal ganglia lesions were enrolled. Among the DGMLs in basal ganglia, putamen had significantly higher (P = 0.037) involvement in PACNS than in MS. More importantly, larger lesion sizes in thalamus helps to distinguish PACNS (12.4 +/- 4.3 mm) from MS (7.9 +/- 3.7 mm) (P = 0.006). But using lesions in basal ganglia, researchers were unable to differentiate the two disorders. Presently, our study shows that MRI performances of deep gray matter differ between MS and PACNS.

引用

页数：5

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