Bioactive p-terphenyl derivatives from a Cordyceps-colonizing isolate of Gliocladium sp.

被引：62
作者：
Guo, Huijuan
Hu, Hejiao
Liu, Shuchun
Liu, Xingzhong
Zhou, Yuguang
Che, Yongsheng [1 ]
机构：
[1] Chinese Acad Sci, Inst Microbiol, Key Lab Syst Mycol & Lichenol, Beijing 100080, Peoples R China
[2] Chinese Acad Sci, Inst Microbiol, Ctr Bioenergy & Ind Microbiol, Beijing 100080, Peoples R China
[3] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 2007年 / 70卷 / 09期
关键词：
D O I：
10.1021/np070231k
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Gliocladinins A (1) and B (2), two new p-terphenyl derivatives, have been isolated from solid cultures of an isolate of Gliocladium sp. that colonizes Cordyceps sinensis. The structures of these compounds were determined mainly by analysis of their NMR spectroscopic data. In standard disk assays, compounds 1 and 2 showed modest antimicrobial activity against Staphylococcus aureus (ATCC 6538). In addition, these compounds displayed inhibitory effects on the growth of two human tumor cell lines, HeLa and HCT116.
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收藏
页码：1519 / 1521
页数：3
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