Life-threatening thrombotic thrombocytopenic purpura (TTP) in a patient with sickle cell-hemoglobin C disease

被引：17
作者：
Lee, HE
Marder, VJ
Logan, LJ
Friedman, S
Miller, BJ
机构：
[1] Los Angeles Orthoped Hosp, Los Angeles, CA 90007 USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Div Hematol & Med Oncol, Los Angeles, CA USA
[3] Cedars Sinai Med Ctr, Los Angeles, CA USA
来源：
ANNALS OF HEMATOLOGY | 2003年 / 82卷 / 11期
关键词：
thrombotic thrombocytopenic purpura; hemoglobin SC disease; plasma exchange;
D O I：
10.1007/s00277-003-0715-0
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report a patient with hemoglobin sickle cell-hemoglobin C disease who developed the clinical syndrome of thrombotic thrombocytopenic purpura (TTP) during admission for typical acute pain crisis. The potential for multiorgan involvement secondary to vaso-occlusive crisis complicated the diagnosis and overlapped with the patient's clinical presentation of chronic bone pain and hemolytic anemia. Clinical improvement and normalization of laboratory parameters followed rapidly in response to plasma exchange therapy.
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页码：702 / 704
页数：3
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