Obstructive Sleep Apnea and the Risk for Cardiovascular Disease

被引：51
作者：
Kohli, Puja [1 ]
Balachandran, Jay S. [1 ]
Malhotra, Atul [1 ]
机构：
[1] Brigham & Womens Hosp, Brookline, MA 02446 USA
来源：
CURRENT ATHEROSCLEROSIS REPORTS | 2011年 / 13卷 / 02期
基金：
美国国家卫生研究院;
关键词：
Lung; Heart; Sleep apnea; Cardiovascular; Hypoxemia; Vascular; POSITIVE AIRWAY PRESSURE; BLOOD-PRESSURE; HEART-FAILURE; PULMONARY-HYPERTENSION; OBESE-PATIENTS; EPIDEMIOLOGY; ASSOCIATION; STROKE; PREVALENCE; MECHANISMS;
D O I：
10.1007/s11883-011-0161-8
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Obstructive sleep apnea (OSA) is a common disorder with major neurocognitive and cardiovascular sequelae. It is estimated that more than one quarter of the population is at risk for OSA, with increased prevalence noted in populations with hypertension, coronary artery disease, stroke, and atrial fibrillation. A number of epidemiologic and mechanistic studies have recently generated interest in the role of OSA in the pathophysiology of cardiovascular disease, a link that continues to require extensive investigation. This chapter reviews these epidemiologic studies, the current understanding of the mechanisms by which OSA may contribute to the progression of cardiovascular diseases, and the effects of OSA treatment on cardiovascular disease outcomes.
引用
收藏
页码：138 / 146
页数：9
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