Cytotoxic cycloartanes from Aglaia argentea

被引：20

作者：

Omobuwajo, OR

Martin, MT

Perromat, G

Sevenet, T

Awang, K

Pais, M

机构：

[1] CNRS, INST CHIM SUBST NAT, F-91198 GIF SUR YVETTE, FRANCE

[2] UNIV MALAYA, DEPT CHEM, KUALA LUMPUR 59100, MALAYSIA

来源：

PHYTOCHEMISTRY | 1996年 / 41卷 / 05期

关键词：

Aglaia argentea; Meliaceae; cycloartane; triterpenoid; cytotoxicity; structural elucidation;

D O I：

10.1016/0031-9422(95)00745-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Aglaia argentea leaves yielded three new cycloartanes: argenteanones A and B, and argenteanol. The first two possess cytotoxic activity against KB cells (IC(50)7.5 mu g ml(-1) and 6.5 mu g ml(-1) respectively). Structural elucidation was done by two-dimensional NMR spectroscopy.

引用

页码：1325 / 1328

页数：4

共 7 条

[1]

BAKRISHNA K, 1990, J NAT PRODUCTS, V53, P523

[2] C-13 AND PROTON NUCLEAR MAGNETIC-RESONANCE STUDIES ON METHYL ALDOFURANOSIDES AND THEIR O-ALKYL DERIVATIVES [J].