Longitudinal evaluation of periodontitis and development of cognitive decline among older adults

被引：25
作者：
Nilsson, Helena [1 ]
Berglund, Johan Sanmartin [2 ,3 ]
Renvert, Stefan [2 ,4 ,5 ]
机构：
[1] Halland Hosp, Maxillofacial Unit, Halmstad, Sweden
[2] Blekinge Inst Technol, Karlskrona, Sweden
[3] Lund Univ, Dept Clin Sci, Lund, Sweden
[4] Kristianstad Univ, Sch Hlth & Soc, Kristianstad, Sweden
[5] Trinity Coll Dublin, Sch Dent Sci, Dublin, Ireland
来源：
JOURNAL OF CLINICAL PERIODONTOLOGY | 2018年 / 45卷 / 10期
关键词：
epidemiology; inflammation; neurocognitive disorders; older adults; periodontal diseases; MINI-MENTAL-STATE; ALZHEIMERS-DISEASE; ORAL-HEALTH; GLOBAL PREVALENCE; TOOTH LOSS; DEMENTIA; HYGIENE; IMPAIRMENT; ALCOHOL; PEOPLE;
D O I：
10.1111/jcpe.12992
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Aim To determine whether having periodontitis is associated with cognitive decline among older adults. Material and MethodsResultsA prospective population study of older adults, Swedish National Study on Ageing and Care, (SNAC) provided repeated registrations of cognitive functions. Cognitive decline was defined as 3-points deterioration from a predetermined level at baseline, using the Mini-Mental State Examination (MMSE). Between 2001 and 2003, 715 individuals had a medical as well as a clinical and radiographic dental examination. The individuals were re-examined after 6years. Periodontitis was defined as 4mm bone loss at 30% of tooth sites. Social variables were captured from questionnaires. The multivariate logistic regression analysis demonstrated a statistically significant association between prevalence of periodontitis and cognitive decline after adjustments of confounding factors of importance. ConclusionsA history of periodontitis may be of importance for cognitive functions among older adults.
引用
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页码：1142 / 1149
页数：8
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