共 39 条
- [1] Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide BiosynthesisJOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (05) : 2027 - 2040Ravindra, ManasaWallace-Povirk, AdrianneKarim, Mohammad A.Wilson, Mike R.O'Connor, CarrieWhite, KathrynKushner, JuiwannaPolin, LisaGeorge, ChristinaHou, ZhanjunMatherly, Larry H.Gangjee, Aleem
- [2] Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide BiosynthesisJOURNAL OF MEDICINAL CHEMISTRY, 2016, 59 (17) : 7856 - 7876Golani, Lalit K.Wallace-Povirk, AdrianneDeis, Siobhan M.Wong, JenniferKe, JiyuanGu, XinRaghavan, SudhirWilson, Mike R.Li, XinxinPoling, Lisade Waal, Parker W.White, KathrynKushnerP, JuiwannaO'Connor, CarrieHou, ZhanjunXu, H. EricMelcher, KarstenDann, Charles E., IIIMatherly, Larry H.Gangjee, Aleem
- [3] Tumor-targeting with novel 6-substituted thienoyl[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α, and inhibition of de novo purine nucleotide biosynthesisCANCER RESEARCH, 2015, 75Matherly, Larry H.Zhang, XinWallace, AdrianneHou, ZhanjunGeorge, ChristinaZhou, XilinGangjee, Aleem
- [4] Fluorine -Substituted Pyrrolo[2,3-d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide BiosynthesisJOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (09) : 4228 - 4248Ravindra, ManasaWilson, Mike R.Tong, NianO'Connor, CarrieKarim, MohammadPolin, LisaWallace-Povirk, AdrianneWhite, KathrynKushner, JuiwannaHou, ZhanjunMatherly, Larry H.Gangjee, Aleem
- [5] Tumor-targeting with novel non-benzoyl 6-substituted pyrrolo[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesisCANCER RESEARCH, 2013, 73 (08)Cherian, ChristinaWang, YiqiangMitchell-Ryan, ShermaineOrr, StevenHou, ZhanjunGangjee, AleemMatherly, Larry H.
- [6] Targeting ovarian cancer with novel 6-substituted pyrrolo [2,3-d] pyrimidine fluorinated antifolates via cellular uptake by folate receptor a and the proton-coupled folate transporterCANCER RESEARCH, 2016, 76Wilson, Mike R.Ravindraa, Manasa P.Wallace-Povirk, AdriannePolin, LisaHou, ZhanjunGangjee, AleemMatherly, Larry H.
- [7] Tumor-Targeting with Novel Non-Benzoyl 6-Substituted Straight Chain Pyrrolo[2,3-d]pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and Inhibition of de Novo Purine Nucleotide BiosynthesisJOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (21) : 8684 - 8695Wang, YiqiangCherian, ChristinaOrr, StevenMitchell-Ryan, ShermaineHou, ZhanjunRaghavan, SudhirMatherly, Larry H.Gangjee, Aleem
- [8] Tumor-targeting with novel dual-targeted 6-substituted thieno[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α, and inhibition of de novo purine nucleotide biosynthesisCANCER RESEARCH, 2018, 78 (13)Wallace-Povirk, AdrianneTong, NianO'Connor, CarrieHou, ZhanjunGangjee, AleemMatherly, LarryZhou, Xilin
- [9] Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d] pyrimidine AntifolatesMOLECULAR CANCER THERAPEUTICS, 2017, 16 (05) : 819 - 830Hou, ZhanjunGattoc, LedaO'Connor, CarrieYang, SiWallace-Povirk, AdrianneGeorge, ChristinaOrr, StevePolin, LisaWhite, KathrynKushner, JuiwannaMorris, Robert T.Gangjee, AleemMatherly, Larry H.
- [10] 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human TumorsJOURNAL OF MEDICINAL CHEMISTRY, 2015, 58 (17) : 6938 - 6959Wang, LeiWallace, AdrianneRaghavan, SudhirDeis, Siobhan M.Wilson, Mike R.Yang, SiPolin, LisaWhite, KathrynKushner, JuiwannaOrr, StevenGeorge, ChristinaO'Connor, CarrieHou, ZhanjunMitchell-Ryan, ShermaineDann, Charles E., IIIMatherly, Larry H.Gangjee, Aleem