LocusZoom: regional visualization of genome-wide association scan results

被引：2026

作者：

Pruim, Randall J. ^{[3
]}

Welch, Ryan P. ^{[1
,2
,4
]}

Sanna, Serena ^{[5
]}

Teslovich, Tanya M. ^{[1
,2
]}

Chines, Peter S. ^{[6
]}

Gliedt, Terry P. ^{[1
,2
]}

Boehnke, Michael ^{[1
,2
]}

Abecasis, Goncalo R. ^{[1
,2
]}

Willer, Cristen J. ^{[1
,2
]}

机构：

[1] Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA

[3] Calvin Coll, Dept Math & Stat, Grand Rapids, MI 49546 USA

[4] Univ Michigan, Sch Med, Bioinformat Grad Program, Ann Arbor, MI 48109 USA

[5] Cittadella Univ Monserrato, CNR, INN, I-09042 Cagliari, Italy

[6] NHGRI, NIH, Bethesda, MD 20892 USA

来源：

BIOINFORMATICS | 2010年 / 26卷 / 18期

关键词：

COMMON VARIANTS; IDENTIFICATION; SNPS; TOOL;

D O I：

10.1093/bioinformatics/btq419

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Genome-wide association studies (GWAS) have revealed hundreds of loci associated with common human genetic diseases and traits. We have developed a web-based plotting tool that provides fast visual display of GWAS results in a publication-ready format. LocusZoom visually displays regional information such as the strength and extent of the association signal relative to genomic position, local linkage disequilibrium (LD) and recombination patterns and the positions of genes in the region.

引用

页码：2336 / 2337

页数：2

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