Electronic nature of N-heterocyclic carbene ligands: Effect on the Suzuki reaction

被引：174

作者：

Hadei, N ^{[1
]}

Kantchev, EAB ^{[1
]}

O'Brien, CJ ^{[1
]}

Organ, MG ^{[1
]}

机构：

[1] York Univ, Dept Chem, Toronto, ON M3J 1P3, Canada

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 10期

关键词：

D O I：

10.1021/ol050471w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Suzuki reactions of aryl chlorides and arylboronic acids with a range of electronically different N-heterocyclic carbene ligands derived from N,N-diadamantylbenzimidazolium salts are reported. Results indicate that an electron-rich NHC ligand enhances the rate of oxidative addition. However, reductive elimination is unchanged by the electronic nature of the supporting ligand and is primarily affected by the steric environment.

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页码：1991 / 1994

页数：4

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