Multifunctional Yolk-Shell Structured Magnetic Mesoporous Polydopamine/Carbon Microspheres for Photothermal Therapy and Heterogenous Catalysis

Yolk-shell structure with magnetic core, interior void and mesoporous polymer/carbon shell demonstrate potential applications in biocatalysis, magnetic biological separation, biomedicine, and magnetic resonance imaging due to their comprehensive benefits of magnetic and mesoporous shells. Herein, yolk-shell structured magnetic mesoporous polydopamine microspheres (Fe3O4@Void@mPDA) and the corresponding derivatives of carbon-based microspheres (Fe3O4@Void@mCN) are successfully fabricated through an interface assembly and selective etching approach. The obtained monodisperse Fe3O4@Void@mPDA microspheres consist of a magnetic core, a mesoporous polydopamine shell, and the large void formed between them, with perpendicular mesopores (5.2 nm), high surface area (303.3 m(2)g(-1)), and richness of functional groups. The Fe3O4@Void@mPDA microspheres show a remarkable inhibitory effect on tumor cells. Moreover, the Fe3O4@Void@ mCN microspheres can immobilize ultrafine Au nanoparticles for hydrogenation of 4-nitrophenol with superb catalytic activity and excellent magnetic reusability.