Injectable calcium phosphate cement as a graft material for maxillary sinus augmentation:: an experimental pilot study

被引:30
作者
Aral, Ali [1 ]
Yalcin, Serdar [1 ]
Karabuda, Zihni Cuneyt [1 ]
Anil, Ata [2 ]
Jansen, John A. [4 ]
Mutlu, Zihni [3 ]
机构
[1] Istanbul Univ, Fac Dent, Dept Oral Implantol, Istanbul, Turkey
[2] Charite Univ Med Berlin, Univ Sch Dent Med, Dept Operat Dent & Periodontol, D-13353 Berlin, Germany
[3] Istanbul Univ, Fac Med Vet, Dept Surg, Istanbul, Turkey
[4] Radboud Univ Nijmegen, Dept Periodontol & Biomat, NL-6525 ED Nijmegen, Netherlands
关键词
autologous bone; bone-implant contact; calcium phosphate cement; sinus elevation;
D O I
10.1111/j.1600-0501.2007.01518.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Objectives: The aim of the present study was to evaluate the efficiency of injectable CaP cement as a graft material around dental implants in the maxillary sinus augmentation procedure. Material and methods: Bilateral sinus augmentation process was carried out in three sheep and two implants were inserted during the same session. Out of a total of 12 installed implants, eight belonged to the so-called experimental group. In the experimental group, injectable CaP cement was used as augmentation material while autologous bone served as control. Results: Histological examination revealed that newly formed bone surrounded the cement completely without an intervening fibrous tissue layer. Following a healing period of 12 weeks, mean bone-to-implant contact (BIC) values in the experimental and control groups were 36 +/- 5 and 37 +/- 3, respectively. The percentage of BIC was comparable with other experimental sinus augmentation studies. Further, it appeared that the thickness of the cortical bone that covered the outer surface of the maxillary sinus was < 2-3 mm, which affected the primary stability of the implants negatively. Conclusion: CaP cement is indeed effective to stimulate bone formation in the sinus elevation procedure. Nevertheless, additional improvements in the cement composition are required to allow final clinical utilization of the material.
引用
收藏
页码:612 / 617
页数:6
相关论文
共 32 条
[1]  
BOYNE PJ, 1980, J ORAL SURG, V38, P613
[2]  
BROWN WE, 1983, J DENT RES, V62, P62
[3]   Injectable calcium phosphate cement as a filler for bone defects around oral implants: an experimental study in goats [J].
Comuzzi, L ;
Ooms, E ;
Jansen, JA .
CLINICAL ORAL IMPLANTS RESEARCH, 2002, 13 (03) :304-311
[4]   SKELETAL REPAIR BY IN-SITU FORMATION OF THE MINERAL PHASE OF BONE [J].
CONSTANTZ, BR ;
ISON, IC ;
FULMER, MT ;
POSER, RD ;
SMITH, ST ;
VANWAGONER, M ;
ROSS, J ;
GOLDSTEIN, SA ;
JUPITER, JB ;
ROSENTHAL, DI .
SCIENCE, 1995, 267 (5205) :1796-1799
[5]   In vivo bone response to porous calcium phosphate cement [J].
del Real, RP ;
Ooms, E ;
Wolke, JGC ;
Vallet-Regí, M ;
Jansen, JA .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2003, 65A (01) :30-36
[6]   11-YEAR STUDY OF HYDROXYAPATITE IMPLANTS [J].
DENISSEN, HW ;
KALK, W ;
VELDHUIS, AAH ;
VANDENHOOFF, A .
JOURNAL OF PROSTHETIC DENTISTRY, 1989, 61 (06) :706-712
[7]   FORMULATION AND SETTING TIMES OF SOME CALCIUM ORTHOPHOSPHATE CEMENTS - A PILOT-STUDY [J].
DRIESSENS, FCM ;
BOLTONG, MG ;
BERMUDEZ, O ;
PLANELL, JA .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 1993, 4 (05) :503-508
[8]   Biomechanical and histological evaluation of a calcium phosphate cement [J].
Frankenburg, EP ;
Goldstein, SA ;
Bauer, TW ;
Harris, SA ;
Poser, RD .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1998, 80A (08) :1112-1124
[9]  
Haas R, 2002, INT J ORAL MAX IMPL, V17, P337
[10]  
HJORTING-HANSEN E, 1990, International Journal of Oral and Maxillofacial Implants, V5, P255