In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography

被引：38
作者：
Sudkamp, Helge [1 ,2 ]
Koch, Peter [1 ]
Spahr, Hendrik [1 ,2 ]
Hillmann, Dierck [3 ]
Franke, Gesa [1 ,2 ]
Muenst, Michael [1 ]
Reinholz, Fred [1 ,2 ]
Birngruber, Reginald [1 ,2 ]
Huettmann, Gereon [1 ,2 ,4 ]
机构：
[1] Med Laser Ctr Lubeck GmbH, Peter Monnik Weg 4, D-23562 Lubeck, Germany
[2] Univ Lubeck, Inst Biomed Opt, Peter Monnik Weg 4, D-23562 Lubeck, Germany
[3] Thorlabs GmbH, Maria Goeppert Str 9, D-23562 Lubeck, Germany
[4] Member German Ctr Lung Res DZL, ARCN, D-35392 Giessen, Germany
来源：
OPTICS LETTERS | 2016年 / 41卷 / 21期
关键词：
ANTERIOR; OCT;
D O I：
10.1364/OL.41.004987
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
With a simple setup, mainly composed of a low coherence light source and a camera, full-field optical coherence tomography (FF-OCT) allows volumetric tissue imaging. However, fringe washout constrains its use in retinal imaging. Here, we present a novel motion-insensitive approach to FF-OCT, which introduces path-length differences between the reference and the sample light in neighboring pixels using an off-axis reference beam. The temporal carrier frequency in scanned time-domain OCT is replaced by a spatial carrier frequency. Volumetric in-vivo FF-OCT measurements of the human retina were acquired in only 1.3 s, comparable to the acquisition times of current clinically used OCT devices. (C) 2016 Optical Society of America
引用
收藏
页码：4987 / 4990
页数：4
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