Microfluidic Encapsulation of Cells in Polymer Microgels

被引：227

作者：

Velasco, Diego ^{[1
]}

Tumarkin, Ethan ^{[1
]}

Kumacheva, Eugenia ^{[1
,2
,3
]}

机构：

[1] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada

[2] Univ Toronto, Inst Biomat & Biomed Engn, Toronto, ON M5S 3G9, Canada

[3] Univ Toronto, Dept Chem Engn & Appl Chem, Toronto, ON M5S 3E5, Canada

来源：

SMALL | 2012年 / 8卷 / 11期

基金：

加拿大自然科学与工程研究理事会;

关键词：

microfluidics; high-throughput techniques; cell encapsulation; microgels; biopolymers; HIGH-THROUGHPUT ENCAPSULATION; MESENCHYMAL STEM-CELLS; SINGLE-CELLS; FOCUSING DEVICE; HYDROGELS; MICROCAPSULES; FABRICATION; GENERATION; MICROBEADS; PARTICLES;

D O I：

10.1002/smll.201102464

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this Concept article, recent advances in microfluidic platforms for the generation of cell-laden hydrogel particles (microgels) are reported. Advances in the continuous microfluidic encapsulation of cells in droplets and microgels are critically reviewed, and currently used methods for the encapsulation of cells in polymer microgels are discussed. An outlook on current applications and future directions in this field of research are also presented. This article will be of interest to chemists, materials scientists, cell biologists, bioengineers, and pharmacologists.

引用

页码：1633 / 1642

页数：10

共 71 条

[1] Sickling of red blood cells through rapid oxygen exchange in microfluidic drops [J].