Prevalence of brain metastases immediately before prophylactic cranial irradiation in limited disease small cell lung cancer patients with complete remission to chemoradiotherapy: A single institution experience

被引：54

作者：

Manapov, Farkhat ^{[1
]}

Klautke, Gunther ^{[1
]}

Fietkau, Rainer ^{[2
]}

机构：

[1] Univ Rostock, Dept Radiotherapy, Fac Med, D-2500 Rostock 1, Germany

[2] Univ Erlangen Nurnberg, Fak Med, Dept Radiotherapy, D-91054 Erlangen, Germany

来源：

JOURNAL OF THORACIC ONCOLOGY | 2008年 / 3卷 / 06期

关键词：

prophylactic cranial irradiation; small cell lung cancer;

D O I：

10.1097/JTO.0b013e3181757a76

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This single-center study investigated the prevalence of brain metastases immediately before prophylactic cranial irradiation in 40 consecutive limited disease small cell lung cancer complete responders to chemoradiotherapy and revealed that 13/40 (32.5%; 95% confidence interval: 18-47%) patients suffer relapse with brain metastases and show a significantly worse prognosis than those without detected brain metastases.

引用

页码：652 / 655

页数：4

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