Differential neural responses to acupuncture revealed by MEG using wavelet-based time-frequency analysis: A pilot study

被引：0

作者：

You, Youbo ^{[1
]}

Bai, Lijun ^{[1
]}

Dai, Ruwei ^{[1
]}

Xue, Ting ^{[1
]}

Zhong, Chongguang ^{[1
]}

Feng, Yuanyuan ^{[1
]}

Wang, Hu ^{[1
]}

Liu, Zhenyu ^{[1
]}

Tian, Jie ^{[1
]}

机构：

[1] Chinese Acad Sci, Intelligent Med Res Ctr, Inst Automat, Beijing, Peoples R China

来源：

2011 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) | 2011年

关键词：

FUNCTIONAL CONNECTIVITY; HUMAN BRAIN; FMRI; STIMULATION; SPECIFICITY; MODULATION; ACTIVATION; ACUPOINTS; DISEASE; CORTEX;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Acupoint specificity, lying at the core of the Traditional Chinese Medicine, still faces many controversies. As previous neuroimaging studies on acupuncture mainly adopted relatively low time-resolution functional magnetic resonance imaging (fMRI) technology and inappropriate block-designed experimental paradigm due to sustained effect, in the current study, we employed a single block-designed paradigm together with high temporal-resolution magnetoencephalography (MEG) technology. We applied time-frequency analysis based upon Morlet wavelet transforming approach to detect differential oscillatory brain dynamics induced by acupuncture at Stomach Meridian 36 (ST36) using a nearby nonacupoint (NAP) as control condition. We observed that frequency power changes were mainly restricted to delta band for both ST36 group and NAP group. Consistently increased delta band power in contralateral temporal regions and decreased power in the counterparts of ipsilateral hemisphere were detected following stimulation at ST36 on the right leg. Compared with ST36, no significant delta ranges were found in temporal regions in NAP group, illustrating different oscillatory brain patterns. Our results may provide additional evidence to support the specificity of acupuncture modulation effects.

引用

页码：7099 / 7102

页数：4

共 35 条

[1] THE CONTRIBUTION OF THE AMYGDALA TO NORMAL AND ABNORMAL EMOTIONAL STATES [J].

AGGLETON, JP .

TRENDS IN NEUROSCIENCES, 1993, 16 (08) :328-333

[2]

[Anonymous], 1998, JAMA, V280, P1518

[3] Acupuncture modulates temporal neural responses in wide brain networks: evidence from fMRI study [J].

Bai, Lijun ;

Tian, Jie ;

Zhong, Chongguang ;

Xue, Ting ;

You, Youbo ;

Liu, Zhenyu ;

Chen, Peng ;

Gong, Qiyong ;

Ai, Lin ;

Qin, Wei ;

Dai, Jianping ;

Liu, Yijun .

MOLECULAR PAIN, 2010, 6

[4] Neural Specificity of Acupuncture Stimulation at Pericardium 6: Evidence From an FMRI Study [J].

Bai, Lijun ;

Yan, Hao ;

Li, Linling ;

Qin, Wei ;

Chen, Peng ;

Liu, Peng ;

Gong, Qiyong ;

Liu, Yijun ;

Tian, Jie .

JOURNAL OF MAGNETIC RESONANCE IMAGING, 2010, 31 (01) :71-77

[5] Spatiotemporal Modulation of Central Neural Pathway Underlying Acupuncture Action: A Systematic Review [J].

Bai, Lijun ;

Qin, Wei ;

Liang, Jimin ;

Tian, Jie ;

Liu, Yijun .

CURRENT MEDICAL IMAGING REVIEWS, 2009, 5 (03) :167-173

[6] Time-Varied Characteristics of Acupuncture Effects in fMRI Studies [J].

Bai, Lijun ;

Qin, Wei ;

Tian, Jie ;

Liu, Peng ;

Li, LinLing ;

Chen, Peng ;

Dai, Jianping ;

Craggs, Jason G. ;

von Deneen, Karen M. ;

Liu, Yijun .

HUMAN BRAIN MAPPING, 2009, 30 (11) :3445-3460

[7] Detection of dynamic brain networks modulated by acupuncture using a graph theory model [J].

Bai, Lijun ;

Qin, Wei ;

Tian, Jie ;

Dai, Jianping ;

Yang, Wanhai .

PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL, 2009, 19 (07) :827-835

[8] Acupuncture modulates spontaneous activities in the anticorrelated resting brain networks [J].

Bai, Lijun ;

Qin, Wei ;

Tian, Jie ;

Dong, Minghao ;

Pan, Xiaohong ;

Chen, Peng ;

Dai, Jianping ;

Yang, Wanhai ;

Liu, Yijun .

BRAIN RESEARCH, 2009, 1279 :37-49

[9]

Baillet S., 1999, NEUROIMAGE, V9, P246

[10]

Beijing S., 1980, NANJING COLL TRADITI

← 1 2 3 4 →