Management of cancer in pregnancy

被引:69
作者
Amant, Frederic [1 ]
Han, Sileny N. [1 ]
Mhallem, Mina [2 ]
Vandenbroucke, Tineke [1 ]
Verheecke, Magali [1 ]
Van Calsteren, Kristel [3 ]
机构
[1] Katholieke Univ Leuven, Dept Obstet & Gynecol, Univ Hosp Leuven, Gynecol Oncol,Dept Oncol, Leuven, Belgium
[2] Clin Univ St Luc, UCL, Dept Obstet & Gynecol, B-1200 Brussels, Belgium
[3] Katholieke Univ Leuven, Univ Hosp Leuven, Dept Obstet & Gynecol, Leuven, Belgium
关键词
pregnancy; cancer; radiotherapy; chemotherapy; surgery; ANTENATAL MATERNAL ANXIETY; CHEMOTHERAPY IN-UTERO; BREAST-CANCER; 1ST TRIMESTER; HEMATOLOGICAL MALIGNANCIES; TRANSPLACENTAL TRANSFER; SURGICAL PROBLEMS; PRETERM CHILDREN; HODGKINS-DISEASE; GESTATIONAL-AGE;
D O I
10.1016/j.bpobgyn.2015.02.006
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
A multidisciplinary discussion is necessary to tackle a complex and infrequent medical problem such as cancer occurring during pregnancy. Pregnancy does not predispose to cancer, but cancers occurring in women of reproductive age are encountered during pregnancy. Ultrasonography and magnetic resonance imaging are the preferred staging examinations, but also a sentinel node staging procedure is possible during pregnancy. Standard cancer treatment is aimed for. Operations can safely be performed during pregnancy, but surgery of genital cancers can be challenging. The observation that chemotherapy administered during the second or third trimester of pregnancy, that is, after the period of organogenesis, has little effect on the long-term outcome of children adds to the therapeutic armamentarium during pregnancy. Cancer treatment during pregnancy adds in the continuation of the pregnancy and the prevention of prematurity. (C) 2015 Published by Elsevier Ltd.
引用
收藏
页码:741 / 753
页数:13
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