Management of cancer in pregnancy

被引：68

作者：

Amant, Frederic ^{[1
]}

Han, Sileny N. ^{[1
]}

Mhallem, Mina ^{[2
]}

Vandenbroucke, Tineke ^{[1
]}

Verheecke, Magali ^{[1
]}

Van Calsteren, Kristel ^{[3
]}

机构：

[1] Katholieke Univ Leuven, Dept Obstet & Gynecol, Univ Hosp Leuven, Gynecol Oncol,Dept Oncol, Leuven, Belgium

[2] Clin Univ St Luc, UCL, Dept Obstet & Gynecol, B-1200 Brussels, Belgium

[3] Katholieke Univ Leuven, Univ Hosp Leuven, Dept Obstet & Gynecol, Leuven, Belgium

来源：

BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY | 2015年 / 29卷 / 05期

关键词：

pregnancy; cancer; radiotherapy; chemotherapy; surgery; ANTENATAL MATERNAL ANXIETY; CHEMOTHERAPY IN-UTERO; BREAST-CANCER; 1ST TRIMESTER; HEMATOLOGICAL MALIGNANCIES; TRANSPLACENTAL TRANSFER; SURGICAL PROBLEMS; PRETERM CHILDREN; HODGKINS-DISEASE; GESTATIONAL-AGE;

D O I：

10.1016/j.bpobgyn.2015.02.006

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A multidisciplinary discussion is necessary to tackle a complex and infrequent medical problem such as cancer occurring during pregnancy. Pregnancy does not predispose to cancer, but cancers occurring in women of reproductive age are encountered during pregnancy. Ultrasonography and magnetic resonance imaging are the preferred staging examinations, but also a sentinel node staging procedure is possible during pregnancy. Standard cancer treatment is aimed for. Operations can safely be performed during pregnancy, but surgery of genital cancers can be challenging. The observation that chemotherapy administered during the second or third trimester of pregnancy, that is, after the period of organogenesis, has little effect on the long-term outcome of children adds to the therapeutic armamentarium during pregnancy. Cancer treatment during pregnancy adds in the continuation of the pregnancy and the prevention of prematurity. (C) 2015 Published by Elsevier Ltd.

引用

页码：741 / 753

页数：13

共 76 条

[21]

DOLL DC, 1989, SEMIN ONCOL, V16, P337

[22] Risk of childhood cancer from fetal irradiation [J].

Doll, R ;

Wakeford, R .

BRITISH JOURNAL OF RADIOLOGY, 1997, 70 :130-139

[23]

Evans SRT, 2012, CURR PROB SURG, V49, P326, DOI [10.1067/j.cpsurg.2012.02.003, 10.1067/j.cpsurg.2012.02.002]

[24]

Gaillard B., 1995, Journal de Gynecologie Obstetrique et Biologie de la Reproduction, V24, P63

[25] Designing pregnancy centered medications: Drugs which do not cross the human placenta [J].

Gedeon, C. ;

Koren, G. .

PLACENTA, 2006, 27 (08) :861-868

[26] DECREASED MINIMUM ALVEOLAR CONCENTRATION OF ISOFLURANE IN PREGNANT HUMANS [J].

GIN, T ;

CHAN, MTV .

ANESTHESIOLOGY, 1994, 81 (04) :829-832

[27] Fear of the unknown: ionizing radiation exposure during pregnancy [J].

Groen, Reinou S. ;

Bae, Jin Y. ;

Lim, Kyoung J. .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2012, 206 (06) :456-462

[28]

GROHARD P, 1989, Journal de Gynecologie Obstetrique et biologie de la Reproduction, V18, P595

[29] Fetal Rat Hearts Do Not Display Acute Cardiotoxicity in Response to Maternal Doxorubicin Treatment [J].

Gziri, Mina Mhallem ;

Pokreisz, Peter ;

De Vos, Rita ;

Verbeken, Eric ;

Debieve, Frederic ;

Mertens, Luc ;

Janssens, Stefan P. ;

Amant, Frederic .

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2013, 346 (03) :362-369

[30] Myocardial function in children after fetal chemotherapy exposure. A tissue Doppler and myocardial deformation imaging study [J].

Gziri, Mina Mhallem ;

Hui, Wei ;

Amant, Frederic ;

Van Calsteren, Kristel ;

Ottevanger, Nelleke ;

Kapusta, Livia ;

Mertens, Luc .

EUROPEAN JOURNAL OF PEDIATRICS, 2013, 172 (02) :163-170

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