Biological properties and activities of major royal jelly proteins and their derived peptides

被引：21

作者：

Muresan, Carmen Ioana ^{[1
]}

Dezmirean, Daniel Severus ^{[2
]}

Marc, Bianca Dana ^{[2
]}

Suharoschi, Ramona ^{[1
]}

Pop, Oana Lelia ^{[1
]}

Buttstedt, Anja ^{[3
]}

机构：

[1] Univ Agr Sci & Vet Med, Fac Food Sci & Technol, Dept Food Sci, Calea Manastur 3-5, Cluj Napoca 400372, Romania

[2] Univ Agr Sci & Vet Med, Fac Anim Breeding & Biotechnol, Calea Manastur 3-5, Cluj Napoca 400372, Cluj, Romania

[3] Univ Pretoria, Dept Zool & Entomol, Social Insects Res Grp, Private Bag X20, ZA-0028 Pretoria, South Africa

来源：

JOURNAL OF FUNCTIONAL FOODS | 2022年 / 98卷

关键词：

Royal jelly; MRJPs; Apalbumin; Jelleins; EPIDERMAL-GROWTH-FACTOR; APIS-MELLIFERA; ANTIMICROBIAL ACTIVITY; ANTIBACTERIAL ACTIVITY; LIFE-SPAN; IN-VITRO; HONEY; GLYCOPROTEIN; REVEALS; IDENTIFICATION;

D O I：

10.1016/j.jff.2022.105286

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Royal jelly (RJ) is a complex beehive product that is important for larval development and queen nutrition in the hive and may also have beneficial effects on human health, according to in vitro and in vivo studies. The main proteins in RJ belong to the Major royal jelly proteins family (MRJPs), representing up to 90% of the total proteins. This narrative review aims to compile the results of studies on MRJPs and their derived peptides to understand their biological effects better, their most important activities being antioxidant, antimicrobial, anti-tumor, hypotensive, hypolipidemic, cell growth promoting, wound healing, anti-aging, neuroprotective, anti-inflammatory and immune-modulatory.

引用

页数：9

共 105 条

[1] Two purified proteins from royal jelly with in vitro dual anti-hepatic damage potency: Major royal jelly protein 2 and its novel isoform X1 [J].

Abu-Serie, Marwa M. ;

Habashy, Noha H. .

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 128 :782-795

[2] New Insights into the Biological and Pharmaceutical Properties of Royal Jelly [J].

Ahmad, Saboor ;

Campos, Maria Graca ;

Fratini, Filippo ;

Altaye, Solomon Zewdu ;

Li, Jianke .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (02)

[3]

[Anonymous], 1792, Nouvelles observations sur les abeilles

[4] Nematicidal activity of 'major royal jelly protein'-containing glycoproteins from Acacia honey [J].

Bilal, Bushra ;

Azim, M. Kamran .

EXPERIMENTAL PARASITOLOGY, 2018, 192 :52-59

[5] New Criterion for Evaluation of Honey: Quantification of Royal Jelly Protein Apalbumin 1 in Honey by ELISA [J].

Bilikova, Katarina ;

Simuth, Jozef .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (15) :8776-8781

[6] Towards functional proteomics of minority component of honeybee royal jelly: The effect of post-translational modifications on the antimicrobial activity of apalbumin2 [J].

Bilikova, Katarina ;

Mirgorodskaya, Ekaterina ;

Bukovska, Gabriela ;

Gobom, Johan ;

Lehrach, Hans ;

Simuth, Jozef .

PROTEOMICS, 2009, 9 (08) :2131-2138

[7] Sequence and structure-based prediction of eukaryotic protein phosphorylation sites [J].

Blom, N ;

Gammeltoft, S ;

Brunak, S .

JOURNAL OF MOLECULAR BIOLOGY, 1999, 294 (05) :1351-1362

[8]

Borchardt L., 1900, Z A GYPTISCHE SPRACH, V38, P94, DOI [10.1524/ZAES.1900.38.JG.94, DOI 10.1524/ZAES.1900.38.JG.94]

[9] Basement membranes in skin: unique matrix structures with diverse functions? [J].

Breitkreutz, Dirk ;

Mirancea, Nicolae ;

Nischt, Roswitha .

HISTOCHEMISTRY AND CELL BIOLOGY, 2009, 132 (01) :1-10

[10] MRJP1-containing glycoproteins isolated from honey, a novel antibacterial drug candidate with broad spectrum activity against multi-drug resistant clinical isolates [J].

Brudzynski, Katrina ;

Sjaarda, Calvin ;

Lannigan, Robert .

FRONTIERS IN MICROBIOLOGY, 2015, 6

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