Role of homocysteine metabolism in animal reproduction: A review

被引:10
作者
Rizzo, A. [1 ]
Sciorsci, R. L. [1 ]
机构
[1] Univ Bari Aldo Moro, Sect Obstet Clin, Dept Vet Med, SP Casamassima Km 3, I-70010 Valenzano, BA, Italy
关键词
Homocysteine; Reproduction; Animals; PLASMA TOTAL HOMOCYSTEINE; FED DIETARY-SUPPLEMENTS; FOLIC-ACID; DAIRY-COWS; B-VITAMIN; OXIDATIVE STRESS; IN-VITRO; CONGENITAL-DEFECTS; SERUM HOMOCYSTEINE; RISK-FACTOR;
D O I
10.1016/j.rvsc.2018.11.011
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Homocysteine (Hcy) is a thiol-containing essential amino acid, important for the growth of cells and tissues. Several hypotheses exist regarding Hcy toxicity in humans; Hcy is involved in protein structural modifications, oxidative stress, and neurotoxicity induction and is therefore associated with several pathological conditions in humans. In veterinary science, knowledge regarding Hcy has increased recently due to several studies; however, many aspects remain undiscovered. Many details remain unknown regarding the effect of Hcy levels on pregnancy and the optimal management of pathological conditions associated with Hcy levels during pregnancy in various species. In this review, we aimed to compile various studies on Hcy metabolism to elucidate its current status in the veterinary field, particularly for ovine, bovine, equine, porcine, canine, and feline species.
引用
收藏
页码:29 / 35
页数:7
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