Palladium-mediated regiodivergent kinetic resolution

被引：18
作者：
Cook, GR [1 ]
Sankaranarayanan, S [1 ]
机构：
[1] N Dakota State Univ, Dept Chem, Fargo, ND 58105 USA
来源：
ORGANIC LETTERS | 2001年 / 3卷 / 22期
关键词：
D O I：
10.1021/ol016633f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] The allylic substitution of racemic 5-vinyloxazolidinones with phthalimide and a chiral palladium catalyst afforded optically enriched regioisomeric products. Optimal divergence was found by employing chiral DIOP ligands in toluene. These results demonstrate the influence of chiral ligand/chiral substrate matching on the regloselectivity in a novel resolution strategy.
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收藏
页码：3531 / 3533
页数：3
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