Integrated analytical sensors: the use of the TISPR-1 as a biosensor

被引：50

作者：

Elkind, JL ^{[1
]}

Stimpson, DI ^{[1
]}

Strong, AA ^{[1
]}

Bartholomew, DU ^{[1
]}

Melendez, JL ^{[1
]}

机构：

[1] Texas Instruments Inc, Dallas, TX 75265 USA

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 1999年 / 54卷 / 1-2期

关键词：

biosensor; SPR; bio-film; assay; distributed sensing;

D O I：

10.1016/S0925-4005(98)00336-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The TISPR-1 integrated surface plasmon resonance (SPR) sensor has features that make it ideal for use in a distributed sensor environment. This sensor, combined with simple bio-films, is shown to be capable of a wide variety of bio-assays. Data for a direct-binding assay for creatine kinase MB (CK-MB), for a displacement assay for dinitrophenol-glycine (DNP-GLY) and a competition assay for trinitrotoluene (TNT) are presented. Also, current and projected TISPR-1 sensor system limits of detection are discussed. (C) 1999 Elsevier Science S.A. All rights reserved.

引用

页码：182 / 190

页数：9

共 26 条

[1] FORMATION OF MONOLAYER FILMS BY THE SPONTANEOUS ASSEMBLY OF ORGANIC THIOLS FROM SOLUTION ONTO GOLD [J].