Integrated analytical sensors: the use of the TISPR-1 as a biosensor

被引：50
作者：
Elkind, JL [1 ]
Stimpson, DI [1 ]
Strong, AA [1 ]
Bartholomew, DU [1 ]
Melendez, JL [1 ]
机构：
[1] Texas Instruments Inc, Dallas, TX 75265 USA
来源：
SENSORS AND ACTUATORS B-CHEMICAL | 1999年 / 54卷 / 1-2期
关键词：
biosensor; SPR; bio-film; assay; distributed sensing;
D O I：
10.1016/S0925-4005(98)00336-0
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The TISPR-1 integrated surface plasmon resonance (SPR) sensor has features that make it ideal for use in a distributed sensor environment. This sensor, combined with simple bio-films, is shown to be capable of a wide variety of bio-assays. Data for a direct-binding assay for creatine kinase MB (CK-MB), for a displacement assay for dinitrophenol-glycine (DNP-GLY) and a competition assay for trinitrotoluene (TNT) are presented. Also, current and projected TISPR-1 sensor system limits of detection are discussed. (C) 1999 Elsevier Science S.A. All rights reserved.
引用
收藏
页码：182 / 190
页数：9
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