Epidemiology and survival outcomes in stages II and III cutaneous melanoma: a systematic review

被引:37
作者
Miller, Rachael [1 ]
Walker, Sophie [1 ]
Shui, Irene [2 ]
Brandtmuller, Agnes [3 ]
Cadwell, Kevin [1 ]
Scherrer, Emilie [2 ]
机构
[1] PHMR Ltd, Berkeley Works, London, England
[2] Merck & Co Inc, Kenilworth, NJ 07033 USA
[3] MSD Pharma Hungary Ltd, H-1095 Budapest, Hungary
关键词
adjuvant therapy; cancer; cutaneous melanoma; epidemiology; incidence; mortality; skin (melanoma); staging; survival; MALIGNANT-MELANOMA; CLINICAL PRESENTATION; LOCALIZED MELANOMA; PRIMARY SITE; FOLLOW-UP; TUMOR; RATES; SURVEILLANCE; DISPARITIES; METASTASES;
D O I
10.2217/mmt-2019-0022
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Aim: Management of cutaneous melanoma (CM) is continually evolving with adjuvant treatment of earlier stage disease. The aim of this review was to identify published epidemiological data for stages II-III CM. Materials & methods: Systematic searches of Medline and Embase were conducted to identify literature reporting country/region-specific incidence, prevalence, survival or mortality outcomes in stage II and/or III CM. Screening was carried out by two independent reviewers. Results & conclusion: Of 41 publications, 14 described incidence outcomes (incidence rates per stage were only reported for US and Swedish studies), 33 reported survival or mortality outcomes and none reported prevalence data. This review summarizes relevant data from published literature and highlights an overall paucity of epidemiological data in stages II and III CM.
引用
收藏
页码:39 / 52
页数:14
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