Evidence based whole breast hypo-fractionated radiation therapy in patients with early breast cancer

被引:0
作者
Koukourakis, Georgios [1 ]
Zacharias, Georgios [2 ]
Petridis, Aristides [3 ]
机构
[1] St Savvas Anticanc Inst Athens, Dept Radiat Therapy, Athens, Greece
[2] Panarcadian Gen Hosp, Hematol Lab, Tripolis, Greece
[3] Metaxa Canc Hosp Piraeus, Dept Radiat Therapy, Piraeus, Greece
来源
JOURNAL OF BUON | 2015年 / 20卷 / 02期
关键词
early breast cancer; evidence; hypo-fractionation; radiation therapy; AMERICAN SOCIETY; RADIOTHERAPY; IRRADIATION; SURVIVAL; TRIAL; TRENDS; WOMEN; TIME;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: The aim of the current study was to evaluate the efficacy and tolerability of hypo-fractionated whole breast radiation therapy in patients with early breast cancer. Methods: Searching electronically PubMed and the Cochrane Central Register we made a comprehensive literature review regarding the randomized controlled phase III trials for hypo-fractionated radiation therapy in early breast cancer. Results: The collected and analyzed data showed that a short course of hypo-fractionated radiation therapy in early breast cancer patients is as effective as the conventional long course regarding tumor response as well as long term side effects. Conclusion: More data are needed about the usage and integration of a boost treatment for higher-risk women receiving neo-adjuvant or adjuvant chemotherapy, or the results in special subgroups such as women with large breast size.
引用
收藏
页码:473 / 478
页数:6
相关论文
共 27 条
[1]  
[Anonymous], 2020, CA Cancer J Clin, DOI DOI 10.3322/CAAC.21590
[2]   Disparities in breast cancer mortality trends between 30 European countries: retrospective trend analysis of WHO mortality database [J].
Autier, Philippe ;
Boniol, Mathieu ;
LaVecchia, Carlo ;
Vatten, Lars ;
Gavin, Anna ;
Hery, Clarisse ;
Heanue, Mary .
BMJ-BRITISH MEDICAL JOURNAL, 2010, 341 :335
[3]   Accelerated Partial Breast Irradiation [J].
Beitsch, Peter D. ;
Shaitelman, Simona F. ;
Vicini, Frank A. .
JOURNAL OF SURGICAL ONCOLOGY, 2011, 103 (04) :362-368
[4]  
Bentzen SM, 2008, LANCET, V371, P1098, DOI 10.1016/S0140-6736(08)60348-7
[5]  
Bentzen SM, 2008, LANCET ONCOL, V9, P331, DOI [10.1016/S1470-2045(08)60348-7, 10.1016/S1470-2045(08)70077-9]
[6]   Radiation Therapy for Early-Stage Breast Cancer after Breast-Conserving Surgery [J].
Buchholz, Thomas A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (01) :63-70
[7]   Early-Stage Breast Cancer Treated With 3-Week Accelerated Whole-Breast Radiation Therapy and Concomitant Boost [J].
Chadha, Manjeet ;
Woode, Rudolph ;
Sillanpaa, Jussi ;
Lucido, David ;
Boolbol, Susan K. ;
Kirstein, Laurie ;
Osborne, Michael P. ;
Feldman, Sheldon ;
Harrison, Louis B. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2013, 86 (01) :40-44
[8]   Phase I-II trial of prone accelerated intensity modulated radiation therapy to the breast to optimally spare normal tissue [J].
Formenti, Silvia C. ;
Gidea-Addeo, Daniela ;
Goldberg, Judith D. ;
Roses, Daniel F. ;
Guth, Amber ;
Rosenstein, Barry S. ;
DeWyngaert, Keith J. .
JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (16) :2236-2242
[9]   Four-week course of radiation for breast cancer using hypofractionated intensity modulated radiation therapy with an incorporated boost [J].
Freedman, Gary M. ;
Anderson, Penny R. ;
Goldstein, Lori J. ;
Ma, Chang-Ming ;
Li, Jinsheng ;
Swaby, Ramona F. ;
Litwin, Samuel ;
Watkins-Bruner, Deborah ;
Sigurdson, Elin R. ;
Morrow, Monica .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 68 (02) :347-353
[10]   Survival effects of postmastectomy adjuvant radiation therapy using biologically equivalent doses: A clinical perspective [J].
Gebski, V ;
Lagleva, M ;
Keech, A ;
Simes, J ;
Langlands, AO .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2006, 98 (01) :26-38