"Asymptomatic" Pseudotumors After Metal-on-Metal Hip Resurfacing Arthroplasty

被引:257
作者
Kwon, Young-Min [1 ]
Ostlere, Simon J. [2 ]
McLardy-Smith, Peter [2 ]
Athanasou, Nicholas A. [2 ]
Gill, Harinderjit S. [2 ]
Murray, David W. [2 ]
机构
[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Adult Reconstruct Surg Unit,Dept Orthopaed Surg, Boston, MA 02116 USA
[2] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Nuffield Orthopaed Ctr, Headington, England
关键词
pseudotumors; metal-on-metal; hip resurfacing; metal ions; INFLAMMATORY PSEUDOTUMOR; SURFACE REPLACEMENT; ION LEVELS; COBALT; BEARINGS; DIAMETER; CHROMIUM; BLOOD; SENSITIVITY; COMPONENT;
D O I
10.1016/j.arth.2010.05.030
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Symptomatic abnormal periprosthetic soft-tissue reactions ("pseudotumors") have been reported after metal-on-metal hip resurfacing arthroplasty (MoMHRA). The aims of this study were (1) to determine the prevalence of asymptomatic pseudotumors after MoMHRA and (2) to measure metal ion levels in these patients. A total of 201 hips in 158 patients were evaluated at a mean follow-up of 61 months (range, 36-88) using ultrasound/magnetic resonance imaging and serum/hip aspirate cobalt and chromium measurements. Pseudotumors found in 7 patients (4%) were associated with significantly higher cobalt and chromium levels and inferior functional scores. Elevated levels of cobalt and chromium ions suggest that pseudotumors are associated with increased wear generated from metal-on-metal articulations. Clinicians need to be aware of pseudotumors as a differential diagnosis during clinical evaluation of MoMHRA patients, and further imaging such as ultrasound or magnetic resonance imaging is recommended to confirm the diagnosis.
引用
收藏
页码:511 / 518
页数:8
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