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- [3] Impressive anti-tumor activity of combined erbB1 and erbB2 blockade with OSI-774 (eriotinib; E) and trastuzumab (T) in combination with weekly paclitaxel (P) in patients (pts) with trastuzumab refractory breast cancer in a phase I pharmacokinetics (PK) study. BREAST CANCER RESEARCH AND TREATMENT, 2006, 100 : S68 - S69