RADIOTHERAPY IN SMALL-CELL LUNG CANCER: LESSONS LEARNED AND FUTURE DIRECTIONS

被引：26

作者：

Slotman, Ben J. ^{[1
]}

Senan, Suresh ^{[1
]}

机构：

[1] Vrije Univ Amsterdam Med Ctr, Dept Radiat Oncol, NL-1081 HV Amsterdam, Netherlands

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2011年 / 79卷 / 04期

关键词：

Small-cell lung cancer; Prophylactic Cranial irradiation; Thoracic radiotherapy; PROPHYLACTIC CRANIAL IRRADIATION; COMBINED-MODALITY TREATMENT; THORACIC RADIATION-THERAPY; PHASE-II TRIAL; CONCURRENT CHEMOTHERAPY; COMPLETE REMISSION; BRAIN METASTASES; RANDOMIZED-TRIAL; CARCINOMA; ETOPOSIDE;

D O I：

10.1016/j.ijrobp.2010.10.039

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Although chemotherapy is an essential component in the treatment of small-cell lung cancer, improvements in survival in the past two decades have been mainly achieved by the appropriate application of radiotherapy. The aim of the present study was to review the key developments in thoracic radiotherapy and prophylactic cranial radiotherapy and to discuss the rationale behind key ongoing studies in small-cell lung cancer. (C) 2011 Elsevier Inc.

引用

页码：998 / 1003

页数：6

共 44 条

[11] Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancer [J].

Fried, DB ;

Morris, DE ;

Poole, C ;

Rosenman, JG ;

Halle, JS ;

Detterbeck, FC ;

Hensing, TA ;

Socinski, MA .

JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (23) :4837-4845

[12]

Glantz MJ, 1997, SEMIN ONCOL, V24, P477

[13] HIPPOCAMPAL-SPARING WHOLE-BRAIN RADIOTHERAPY: A "HOW-TO" TECHNIQUE USING HELICAL TOMOTHERAPY AND LINEAR ACCELERATOR-BASED INTENSITY-MODULATED RADIOTHERAPY [J].

Gondi, Vinai ;

Tolakanahalli, Ranjini ;

Mehta, Minesh P. ;

Tewatia, Dinesh ;

Rowley, Howard ;

Kuo, John S. ;

Khuntia, Deepak ;

Tome, Wolfgang A. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 78 (04) :1244-1252

[14] Randomized trial of alternating versus sequential radiotherapy/chemotherapy in limited-disease patients with small-cell lung cancer: A European organization for research and treatment of cancer lung cancer cooperative group study [J].

Gregor, A ;

Drings, P ;

Burghouts, J ;

Postmus, PE ;

Morgan, D ;

Sahmoud, T ;

Kirkpatrick, A ;

Dalesio, O ;

Giaccone, G .

JOURNAL OF CLINICAL ONCOLOGY, 1997, 15 (08) :2840-2849

[15] Prophylactic cranial irradiation is indicated following complete response to induction therapy in small cell lung cancer: Results of a multicentre randomised trial [J].

Gregor, A ;

Cull, A ;

Stephens, RJ ;

Kirkpatrick, JA ;

Yarnold, JR ;

Girling, DJ ;

Macbeth, FR ;

Stout, R ;

Machin, D .

EUROPEAN JOURNAL OF CANCER, 1997, 33 (11) :1752-1758

[16] Role of radiation therapy in the combined-modality treatment of patients with extensive disease small-cell lung cancer: A randomized study [J].

Jeremic, B ;

Shibamoto, Y ;

Nikolic, N ;

Milicic, B ;

Milisavljevic, S ;

Dagovic, A ;

Aleksandrovic, J ;

Radosavljevic-Asic, G .

JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (07) :2092-2099

[17] Initial versus delayed accelerated hyperfractionated radiation therapy and concurrent chemotherapy in limited small-cell lung cancer: A randomized study [J].

Jeremic, B ;

Shibamoto, Y ;

Acimovic, L ;

Milisavljevic, S .

JOURNAL OF CLINICAL ONCOLOGY, 1997, 15 (03) :893-900

[18] Phase I study of thoracic radiation dose escalation with concurrent chemotherapy for patients with limited small-cell lung cancer: Report of Radiation Therapy Oncology Group (RTOG) protocol 97-12 [J].

Komaki, R ;

Swann, RS ;

Ettinger, DS ;

Glisson, BS ;

Sandler, AB ;

Movsas, B ;

Suh, J ;

Byhardt, RW .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2005, 62 (02) :342-350

[19] Patterns of First Failure in a Phase II Study of Accelerated High Dose Thoracic Radiation Therapy (TRT) with Concurrent Chemotherapy for Limited Small-cell Lung Cancer (LSCLC): Radiation Therapy Oncology Group (RTOG) 0239 [J].

Komaki, R. U. ;

Paulus, R. ;

Ettinger, D. ;

Videtic, G. ;

Bradley, J. ;

Glisson, B. ;

Choy, H. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 75 (03) :S34-S35

[20] Trends in the outcomes for patients with limited stage small cell lung cancer: An analysis of the Surveillance, Epidemiology, and End Results database [J].

Lally, Brian E. ;

Geiger, Ann M. ;

Urbanic, James J. ;

Butler, Jerome M. ;

Wentworth, Stacy ;

Perry, Michael C. ;

Wilson, Lynn D. ;

Horton, Janet K. ;

Detterbeck, Frank C. ;

Miller, Antonius A. ;

Thomas, Charles R., Jr. ;

Blackstock, A. William .

LUNG CANCER, 2009, 64 (02) :226-231

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