Error threshold for spatially resolved evolution in the quasispecies model

被引：57

作者：

Altmeyer, S ^{[1
]}

McCaskill, JS ^{[1
]}

机构：

[1] GMD, German Natl Res Ctr Informat Technol, BioMIP, D-53754 St Augustin, Germany

来源：

PHYSICAL REVIEW LETTERS | 2001年 / 86卷 / 25期

关键词：

D O I：

10.1103/PhysRevLett.86.5819

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The error threshold for quasispecies in 1, 2, 3, and infinity dimensions is investigated by stochastic simulation and analytically. The results show a monotonic decrease in the maximal sustainable error probability with decreasing diffusion coefficient, independently of the spatial dimension. it is thereby established that physical interactions between sequences are necessary in order for spatial effects to enhance the stabilization of biological information. The analytically tractable behavior in an infinity -dimensional (simplex) space provides a good guide to the spatial dependence of the error threshold in lower dimensional Euclidean space.

引用

页码：5819 / 5822

页数：4

共 21 条

[1] ABSENCE OF DIFFUSION IN CERTAIN RANDOM LATTICES [J].

ANDERSON, PW .

PHYSICAL REVIEW, 1958, 109 (05) :1492-1505

[2] Ising quantum chain is equivalent to a model of biological evolution [J].

Baake, E ;

Baake, M ;

Wagner, H .

PHYSICAL REVIEW LETTERS, 1997, 78 (03) :559-562

[3] SPIRAL WAVE STRUCTURE IN PRE-BIOTIC EVOLUTION - HYPERCYCLES STABLE AGAINST PARASITES [J].

BOERLIJST, MC ;

HOGEWEG, P .

PHYSICA D, 1991, 48 (01) :17-28

[4]

CABALLERO A, 1995, GENETICS, V139, P1007

[5] Finite-size scaling of the error threshold transition in finite populations [J].

Campos, PRA ;

Fontanari, JF .

JOURNAL OF PHYSICS A-MATHEMATICAL AND GENERAL, 1999, 32 (01) :L1-L7

[6] The variant call format and VCFtools [J].

Danecek, Petr ;

Auton, Adam ;

Abecasis, Goncalo ;

Albers, Cornelis A. ;

Banks, Eric ;

DePristo, Mark A. ;

Handsaker, Robert E. ;

Lunter, Gerton ;

Marth, Gabor T. ;

Sherry, Stephen T. ;

McVean, Gilean ;

Durbin, Richard .

BIOINFORMATICS, 2011, 27 (15) :2156-2158

[7] STOCHASTIC MODELS FOR SECOND-ORDER CHEMICAL REACTION KINETICS . EQUILIBRIUM STATE [J].

DARVEY, IG ;

NINHAM, BW ;

STAFF, PJ .

JOURNAL OF CHEMICAL PHYSICS, 1966, 45 (06) :2145-+

[8] THE IMPORTANCE OF BEING DISCRETE (AND SPATIAL) [J].

DURRETT, R ;

LEVIN, S .

THEORETICAL POPULATION BIOLOGY, 1994, 46 (03) :363-394

[9] SELFORGANIZATION OF MATTER AND EVOLUTION OF BIOLOGICAL MACROMOLECULES [J].

EIGEN, M .

NATURWISSENSCHAFTEN, 1971, 58 (10) :465-+

[10]

EIGEN M, 1989, ADV CHEM PHYS, V75, P149

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