Subcutaneous adipose tissue as a biomarker of pancreatic cancer: A pilot study in male patients

被引：10
作者：
Greco, Federico [1 ,2 ]
Mallio, Carlo Augusto [1 ]
Cirimele, Vincenzo [1 ]
Grasso, Rosario Francesco [1 ]
Zobel, Bruno Beomonte [1 ]
机构：
[1] Univ Campus Biomed Roma, Unit Diagnost Imaging, Via Alvaro Del Portillo 21, I-00128 Rome, Italy
[2] Presidio Osped Orientale M Giannuzzi Manduria, Azienda Sanitaria Locale Taranto, Unit Diagnost Imaging, Via Mandonion 1, I-74024 Manduria, Italy
来源：
CLINICAL CANCER INVESTIGATION JOURNAL | 2019年 / 8卷 / 03期
关键词：
Adrenomedullin; computed tomography; pancreatic cancer; subcutaneous adipose tissue; WEIGHT-LOSS; LIPOLYSIS; LIPASES;
D O I：
10.4103/ccij.ccij_36_19
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Purpose: The purpose of this study was to evaluate the relationship between subcutaneous adipose tissue (SAT) and pancreatic cancer (PC) in male patients. Methods: In this retrospective study, two groups were included. Quantitative assessment of adipose tissue was performed by measuring total adipose tissue (TAT) area, visceral adipose tissue (VAT) area, and the SAT area in both the groups. Then, VAT/SAT ratio was calculated. Results: Statistically significant differences between the two groups were found in the SAT area (P < 0.05), TAT area was slightly above the threshold of significance, while no significant difference was found in the VAT area and VAT/SAT ratio. Conclusions: The results of this study suggest an association between SAT reduction and PC risk.
引用
收藏
页码：114 / 118
页数：5
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