The Role of Genetic Variants in the Susceptibility of Noise-Induced Hearing Loss

被引:16
作者
Chen, Xue-min [1 ,2 ,3 ,4 ,5 ]
Xue, Xin-miao [1 ,2 ,3 ,4 ,5 ]
Yu, Ning [2 ,3 ,4 ,5 ]
Guo, Wei-wei [2 ,3 ,4 ,5 ]
Yuan, Shuo-long [2 ,3 ,4 ,5 ]
Jiang, Qing-qing [2 ,3 ,4 ,5 ]
Yang, Shi-ming [2 ,3 ,4 ,5 ]
机构
[1] Med Sch Chinese PLA, Beijing, Peoples R China
[2] Chinese Peoples Liberat Army Gen Hosp, Sr Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
[3] Natl Clin Res Ctr Otolaryngol Dis, Beijing, Peoples R China
[4] Minist Educ, State Key Lab Hearing Sci, Beijing, Peoples R China
[5] Beijing Key Lab Hearing Impairment Prevent & Treat, Beijing, Peoples R China
基金
中国国家自然科学基金;
关键词
genes; noised-induced hearing loss; noise prevention; susceptibility; genetic variants; MITOCHONDRIAL CELL-DEATH; HAIR-CELL; INCREASES SUSCEPTIBILITY; OXIDATIVE STRESS; LNCRNA HOTAIR; INNER-EAR; TIP-LINK; CAT GENE; ASSOCIATION; POLYMORPHISMS;
D O I
10.3389/fncel.2022.946206
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Noised-induced hearing loss (NIHL) is an acquired, progressive neurological damage caused by exposure to intense noise in various environments including industrial, military and entertaining settings. The prevalence of NIHL is much higher than other occupational injuries in industrialized countries. Recent studies have revealed that genetic factors, together with environmental conditions, also contribute to NIHL. A group of genes which are linked to the susceptibility of NIHL had been uncovered, involving the progression of oxidative stress, potassium ion cycling, cilia structure, heat shock protein 70 (HSP70), DNA damage repair, apoptosis, and some other genes. In this review, we briefly summarized the studies primary in population and some animal researches concerning the susceptible genes of NIHL, intending to give insights into the further exploration of NIHL prevention and individual treatment.
引用
收藏
页数:17
相关论文
共 158 条
[1]   The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15 [J].
Ahmed, Zubair M. ;
Goodyear, Richard ;
Riazuddin, Saima ;
Lagziel, Ayala ;
Legan, P. Kevin ;
Behra, Martine ;
Burgess, Shawn M. ;
Lilley, Kathryn S. ;
Wilcox, Edward R. ;
Riazuddin, Sheikh ;
Griffith, Andrew J. ;
Frolenkov, Gregory I. ;
Belyantseva, Inna A. ;
Richardson, Guy P. ;
Friedman, Thomas B. .
JOURNAL OF NEUROSCIENCE, 2006, 26 (26) :7022-7034
[2]   One Enzyme, Two Functions PON2 PREVENTS MITOCHONDRIAL SUPEROXIDE FORMATION AND APOPTOSIS INDEPENDENT FROM ITS LACTONASE ACTIVITY [J].
Altenhoefer, Sebastian ;
Witte, Ines ;
Teiber, John F. ;
Wilgenbus, Petra ;
Pautz, Andrea ;
Li, Huige ;
Daiber, Andreas ;
Witan, Heidrun ;
Clement, Albrecht M. ;
Foerstermann, Ulrich ;
Horke, Sven .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (32) :24398-24403
[3]   Association Analysis of Candidate Gene Polymorphisms and Audiometric Measures of Noise-Induced Hearing Loss in Young Musicians [J].
Bhatt, Ishan Sunilkumar ;
Dias, Raquel ;
Washnik, Nilesh ;
Wang, Jin ;
Guthrie, O'neil ;
Skelton, Michael ;
Lane, Jeffery ;
Wilder, Jason .
OTOLOGY & NEUROTOLOGY, 2020, 41 (05) :E538-E547
[4]   Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle [J].
Boëda, B ;
El-Amraoui, A ;
Bahloul, A ;
Goodyear, R ;
Daviet, L ;
Blanchard, S ;
Perfettini, I ;
Fath, KR ;
Shorte, S ;
Reiners, J ;
Houdusse, A ;
Legrain, P ;
Wolfrum, U ;
Richardson, G ;
Petit, C .
EMBO JOURNAL, 2002, 21 (24) :6689-6699
[5]   EYA4, a novel vertebrate gene related to Drosophila eyes absent [J].
Borsani, G ;
DeGrandi, A ;
Ballabio, A ;
Bulfone, A ;
Bernard, L ;
Banfi, S ;
Gattuso, C ;
Mariani, M ;
Dixon, M ;
Donnai, D ;
Metcalfe, K ;
Winter, R ;
Robertson, M ;
Axton, R ;
Brown, A ;
van Heyningen, V ;
Hanson, I .
HUMAN MOLECULAR GENETICS, 1999, 8 (01) :11-23
[6]  
Braga MP, 2014, BRAZ J OTORHINOLAR, V80, P373
[7]  
Cao Jing-lian, 2013, Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi, V31, P734
[8]   Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases [J].
Cargnello, Marie ;
Roux, Philippe P. .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 2011, 75 (01) :50-83
[9]   The influence of genetic variation in oxidative stress genes on human noise susceptibility [J].
Carlsson, PI ;
Van Laer, L ;
Borg, E ;
Bondeson, ML ;
Thys, M ;
Fransen, E ;
Van Camp, G .
HEARING RESEARCH, 2005, 202 (1-2) :87-96
[10]  
Carroll YI, 2017, MMWR-MORBID MORTAL W, V66, P139, DOI 10.15585/mmwr.mm6605e3