Symptom and structure modifying properties of chondroitin sulfate in Osteoarthritis

被引:14
作者
Reginster, Jean-Yves [1 ]
Heraud, Florence
Zegels, Brigitte
Bruyere, Olivier
机构
[1] Univ Liege, Dept Publ Hlth Epidemiol & Hlth Econ, Liege, Belgium
[2] Univ Liege, Dept Publ Hlth Econ, Liege, Belgium
[3] Labs Genevrier, F-06901 Sophia Antipolis, France
关键词
chondroitin sulfate; sulfation patterns; cartilage; glycosaminoglycans; osteoarthritis; SYSADOAs;
D O I
10.2174/138955707782110088
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Chondroitin sulfate (CS) is a complex carbohydrate polymer with variable sulfation which impacts function. CS exhibits a wide range of biological activities. Many experimental and clinical data are available, affirming that CS represents an effective and safe symptomatic treatment of osteoarthritis (OA) with delayed and sustained effects.
引用
收藏
页码:1051 / 1061
页数:11
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