Heart Rate Recovery After Exercise Is a Predictor of Silent Myocardial Ischemia in Patients With Type 2 Diabetes

被引：19

作者：

Yamada, Tomohide ^{[1
]}

Yoshitama, Takashi ^{[1
]}

Makino, Kunihiko ^{[1
]}

Lee, Tetsuo ^{[1
]}

Saeki, Fumihiko ^{[1
]}

机构：

[1] Toshiba Hosp, Dept Cardiol, Tokyo, Japan

来源：

DIABETES CARE | 2011年 / 34卷 / 03期

关键词：

MELLITUS; STRESS;

D O I：

10.2337/dc10-1424

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVE-Slow heart rate recovery (HRR) predicts all-cause mortality. This study investigated the relationship between silent myocardial ischemia (SMI) and HRR in type 2 diabetes. RESEARCH DESIGN AND METHODS-The study enrolled 87 consecutive patients with type 2 diabetes and no chest symptoms. They underwent treadmill exercise testing and single-photon emission computed tomography imaging with thallium scintigraphy. Patients with abnormal myocardial perfusion images also underwent coronary angiography. RESULTS-SMI was diagnosed in 41 patients (47%). The SMI group showed slower HRR than the non SMI group (18 +/- 6 vs. 30 +/- 12 bpm; P < 0.0001). HRR was significantly associated with SMI (odds ratio 0.83 [95% Cl 0.75-0.92]; P = 0.0006), even after adjustment for maximal exercise workload, resting heart rate, maximum heart rate, rate pressure product, HbA(1c), use of sulfonamides, and a history of cardiovascular disease. CONCLUSIONS-HRR can predict SMI in patients with type 2 diabetes.

引用

收藏

页码：724 / 726

页数：3

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