PROTOCOL FOR 18F-FDG QUANTIFICATION IN PET-CT WHOLE-BODY EXAMS

被引：11

作者：

Velasques De Oliveira, S. M. ^{[1
]}

Carlos, M. T. ^{[1
]}

Carneiro, M. P. ^{[2
]}

Da Silva, J. W. E. ^{[2
,3
]}

Kasai, E. P. ^{[2
,3
]}

Oliveira, A. R. N. ^{[1
,2
]}

Boasquevisque, E. M. ^{[3
]}

机构：

[1] Inst Radioprotecao & Dosimetria IRD CNEN, BR-22780160 Rio De Janeiro, Brazil

[2] Multi Imagem PET CT, Rio De Janeiro, Brazil

[3] Univ Estado Rio de Janeiro, Fac Ciencias Med, BR-20550011 Rio De Janeiro, Brazil

来源：

CELLULAR AND MOLECULAR BIOLOGY | 2010年 / 56卷 / 02期

关键词：

Positron emission tomography; internal dosimetry; computed tomography; external dosimetry;

D O I：

10.1170/T894

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The aim of the present work is to propose a protocol for quantification of F-18-FDG activities at organ level through whole body exams with Positron Emission Tomography. They were selected patients with normal uptake or a single tumor. In the period 2004-2005, 745 patients were studied. Among then, it was selected 97 adults for the normal uptake control group. The main studies were: intestine; colon, rectum, lung, lymphoma and melanoma, liver, esophagus, gonads and breasts. For "prospective screening", it were selected 20 patients with the identical physical characteristics of the control group. For internal dosimetry, the main organs should be elected according the kinetics of F-18-FDG, either considering normal uptake or pathologies. Absorbed doses due to Computed Tomography and F-FDG uptake were estimated. Comparisons between internal and external exposures, for the same organ, point out higher doses due to external irradiation, except for bladder and kidneys. For individual dose estimation, parameters such the effective half-life should be known and this information may be achieved by an adaptation of the routine protocol.

引用

页码：44 / 46

页数：3

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