Controlling the transport of particles in flowing suspensions at microscale is of interest in numerous contexts such as the development of miniaturized and point-of-care analytical devices (in bioengineering, for foodborne illnesses detection, etc.) and polymer engineering. In square microchannels, neutrally buoyant spherical particles are known to migrate across the flow streamlines and concentrate at specific equilibrium positions located at the channel centerline at low flow inertia and near the four walls along their symmetry planes at moderate Reynolds numbers. Under specific flow and geometrical conditions, the spherical particles are also found to line up in the flow direction and form evenly spaced trains. In order to statistically explore the dynamics of train formation and their dependence on the physical parameters of the suspension flow (particle-to-channel size ratio, Reynolds number and solid volume fraction), experiments have been conducted based on in situ visualizations of the flowing particles by optical microscopy. The trains form only once particles have reached their equilibrium positions (following lateral migration). The percentage of particles in trains and the interparticle distance in a train have been extracted and analyzed. The percentage of particles organized in trains increases with the particle Reynolds number up to a threshold value which depends on the concentration and then decreases for higher values. The average distance between the surfaces of consecutive particles in a train decreases as the particle Reynolds number increases and is independent of the particles size and concentration, if the concentration remains below a threshold value related to the degree of confinement of the suspension flow.
机构:
Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
Calif NanoSyst Inst, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
Amini, Hamed
;
Lee, Wonhee
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Korea Adv Inst Sci & Technol, Grad Sch Nanosci & Technol, Taejon, South KoreaUniv Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
Lee, Wonhee
;
Di Carlo, Dino
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机构:
Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
Calif NanoSyst Inst, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
机构:
Univ Calif Los Angeles, Henry Samueli Sch Engn & Appl Sci, Dept Bioengn, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Henry Samueli Sch Engn & Appl Sci, Calif NanoSyst Inst, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Henry Samueli Sch Engn & Appl Sci, Dept Bioengn, Los Angeles, CA 90095 USA
机构:
Massachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Edd, Jon F.
;
Di Carlo, Dino
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Massachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Di Carlo, Dino
;
Humphry, Katherine J.
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Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Humphry, Katherine J.
;
Koster, Sarah
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机构:
Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Koster, Sarah
;
Irimia, Daniel
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Massachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Irimia, Daniel
;
Weitz, David A.
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机构:
Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Weitz, David A.
;
Toner, Mehmet
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Massachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
机构:
Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
Calif NanoSyst Inst, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
Amini, Hamed
;
Lee, Wonhee
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h-index: 0
机构:
Korea Adv Inst Sci & Technol, Grad Sch Nanosci & Technol, Taejon, South KoreaUniv Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
Lee, Wonhee
;
Di Carlo, Dino
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
Calif NanoSyst Inst, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA
机构:
Univ Calif Los Angeles, Henry Samueli Sch Engn & Appl Sci, Dept Bioengn, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Henry Samueli Sch Engn & Appl Sci, Calif NanoSyst Inst, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Henry Samueli Sch Engn & Appl Sci, Dept Bioengn, Los Angeles, CA 90095 USA
机构:
Massachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Edd, Jon F.
;
Di Carlo, Dino
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Di Carlo, Dino
;
Humphry, Katherine J.
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h-index: 0
机构:
Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Humphry, Katherine J.
;
Koster, Sarah
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Koster, Sarah
;
Irimia, Daniel
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Irimia, Daniel
;
Weitz, David A.
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA
Weitz, David A.
;
Toner, Mehmet
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USAMassachusetts Gen Hosp, BioMEMS Resource Ctr, Charlestown, MA USA