Nucleoid occlusion and bacterial cell division

被引：139

作者：

Wu, Ling Juan ^{[1
]}

Errington, Jeff ^{[1
]}

机构：

[1] Newcastle Univ, Ctr Bacterial Cell Biol, Inst Cell & Mol Biosci, Newcastle Upon Tyne NE2 4AX, Tyne & Wear, England

来源：

NATURE REVIEWS MICROBIOLOGY | 2012年 / 10卷 / 01期

基金：

英国生物技术与生命科学研究理事会; 欧洲研究理事会;

关键词：

ASSEMBLY DYNAMICS; ESCHERICHIA-COLI; FTSZ; PROTEIN; REPLICATION; SITE;

D O I：

10.1038/nrmicro2671

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The bacterial cell cycle requires the tight regulation and precise coordination of several sophisticated cellular processes. Prominent among them is the formation of the dividing wall or septum, which has to take place at the right time and place to ensure equality of the progeny and integrity of the genome. Nucleoid occlusion is a defence mechanism that prevents the chromosome from being bisected and broken by the division septum. It does so by preventing Z ring formation near the nucleoid, which also helps to determine the location of septation.

引用

页码：8 / 12

页数：5

共 25 条

[1] Bacterial cell division: assembly, maintenance and disassembly of the Z ring [J].