Copper-catalyzed direct cross coupling of 1,3,4-oxadiazoles with trans-β-halostyrenes: synthesis of 2-E-vinyl 1,3,4-oxadiazoles

被引：21

作者：

Das, Biswanath ^{[1
]}

Reddy, Gandolla Chinna ^{[1
]}

Balasubramanyam, Penagaluri ^{[1
]}

Salvanna, N. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON | 2012年 / 68卷 / 01期

关键词：

C-H activation; 1,3,4-Oxadiazole; trans-beta-Halostyrenes; Copper iodide; Alkenylation; ALPHA-AMINO PHOSPHONATES; C-H ARYLATION; DIRECT ALKYNYLATION; BOND FORMATION; ALKENYLATION; (HETERO)ARENES; OXAZOLES; DESIGN; AZOLES;

D O I：

10.1016/j.tet.2011.10.049

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first direct C-H alkenylation of 1,3,4-oxadiazoles with trans-beta-halo olefinic system has been carried out using a combination of Cul/DMEDA as a catalyst. A wide range of 2-E-vinyl-substituted oxadiazoles were obtained in high yields (85-93%). (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：300 / 305

页数：6

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