Epidemiology, Microbiology and Severity of Bronchiolitis in the First Post-Lockdown Cold Season in Three Different Geographical Areas in Italy: A Prospective, Observational Study

被引:39
作者
Camporesi, Anna [1 ]
Morello, Rosa [2 ]
Ferro, Valentina [3 ]
Pierantoni, Luca [4 ]
Rocca, Alessandro [4 ]
Lanari, Marcello [4 ]
Trobia, Gian Luca [5 ]
Sciacca, Tiziana [5 ]
Bellinvia, Agata Giuseppina [5 ]
De Ferrari, Alessandra [1 ]
Valentini, Piero [2 ]
Roland, Damian [6 ,7 ]
Buonsenso, Danilo [2 ,8 ]
机构
[1] Vittore Buzzi Childrens Hosp, Anesthesia & Intens Care Unit, I-20154 Milan, Italy
[2] Fdn Policlin Univ A Gemelli IRCCS, Dept Woman & Child Hlth, I-00168 Rome, Italy
[3] Bambin Gesu Childrens Hosp IRCCS, Dept Pediat Emergency, I-00168 Rome, Italy
[4] IRCCS Azienda Osped Univ Bologna, Pediat Emergency Unit, I-40138 Bologna, Italy
[5] Cannizzaro Emergency Hosp Catania, Pediat & Pediat Emergency Room Unit, I-95126 Catania, Italy
[6] Leicester Hosp, Paediat Emergency Med Leicester Acad PEMLA Grp, Leicester LE1 5WWM, Leics, England
[7] Univ Leicester, Social Sci APPl Healthcare Improvement REs, SAPPHIRE Grp, Hlth Sci, Leicester LE1 7RH, Leics, England
[8] Univ Cattolica Sacro Cuore, Ctr Global Hlth Res Studies, I-00168 Rome, Italy
来源
CHILDREN-BASEL | 2022年 / 9卷 / 04期
关键词
bronchiolitis; COVID-19; RSV; respiratory syncytial virus; children; RESPIRATORY SYNCYTIAL VIRUS; PUBLIC-HEALTH MEASURES; INFLUENZA; COVID-19; INTERFERENCE;
D O I
10.3390/children9040491
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The aim of this study was to understand the epidemiology, disease severity, and microbiology of bronchiolitis in Italy during the 2021-2022 cold season, outside of lockdowns. Before COVID-19, the usual bronchiolitis season in Italy would begin in November and end in April, peaking in February. We performed a prospective observational study in four referral pediatric centers located in different geographical areas in Italy (two in the north, one in the center and one in the south). From 1 July 2021 to 31 January 2022, we collected all new clinical diagnoses of bronchiolitis in children younger than two years of age recording demographic, clinical and microbiological data. A total of 657 children with a clinical diagnosis of bronchiolitis were enrolled; 56% children were admitted and 5.9% required PICU admission. The first cases were detected during the summer, peaking in November 2021 and declining into December 2021 with only a few cases detected in January 2022. RSV was the commonest etiological agent, while SARS-CoV-2 was rarely detected and only since the end of December 2021. Disease severity was similar in children with RSV vs. non-RSV bronchiolitis, and in those with a single infectious agent detected compared with children with co-infections. The 2021-2022 bronchiolitis season in Italy started and peaked earlier than the usual pre-pandemic seasons, but had a shorter duration. Importantly, the current bronchiolitis season was not more severe when data were compared with Italian published data, and SARS-CoV-2 was rarely a cause of bronchiolitis in children younger than 24 months of age.
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页数:15
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