Posterior synechiae after Nd:YAG laser iridotomy:: a clinical study

Methods: In 146 eyes/patients who unterwent Nd:YAG laser iridotomy after glaucomatous attack or after prophylactic iridotomy, we evaluated whether the frequency of posterior synechiae depends on (1) glaucomatous attack, (2) preoperative miotic therapy, (3) postoperative antiglaucomatous therapy or (4) mode of intraoperative laser therapy. Out of 616 eyes with YAG iridotomy between 1983 and 1987, 146 eyes/patients fulfilled the inclusion criteria: observation time of minimum 3 months after iridotomy, preoperative examination without signs of preexisting synechiae, postoperative examination at discharge and a later control examination in mydriasis to exclude posterior synechiae. Results: Eyes with and without glaucomatous attack and eyes with and without preoperative long-term miotic therapy showed no significant difference in frequency of posterior synechiae. Eyes with postoperative long-term therapy with miotics or betablockers showed posterior synechiae significantly more often than eyes without postoperative miotic or beta-blocker therapy. Eyes that received DPE in the early postoperative period developed posterior synechiae significantly less often. The number of laser pulses and the mean total energy used were significantly higher in eyes which rarer developed posterior synechiae. in the group of patients with glaucomatous attack women outnumbered men by four to one, but there was no significant difference in refraction between women and men. Conclusions: Patients with glaucomatous attack are not at a higher risk of developing posterior synechiae than those without glaucomatous attack. Post-operative antiglaucomatous therapy, the number of laser pulses and the total energy alter the frequency of postoperatively developed posterior synechiae.