Comparative study of the toxicity between three non-steroidal anti-inflammatory drugs and their UV/Na2S2O8 degradation products on Cyprinus carpio

被引：18

作者：

Gao, Xingsheng ^{[1
]}

Geng, Jinju ^{[1
]}

Du, Yourong ^{[1
]}

Li, Shaoli ^{[1
]}

Wu, Gang ^{[1
]}

Fu, Yingying ^{[1
]}

Ren, Hongqiang ^{[1
]}

机构：

[1] Nanjing Univ, Sch Environm, State Key Lab Pollut Control & Resource Reuse, Nanjing, Jiangsu, Peoples R China

来源：

SCIENTIFIC REPORTS | 2018年 / 8卷

基金：

中国国家自然科学基金;

关键词：

ENVIRONMENTAL RISK-ASSESSMENT; PERSONAL CARE PRODUCTS; WASTE-WATER; ADVANCED OXIDATION; TRANSFORMATION PRODUCTS; ACIDIC PHARMACEUTICALS; IBUPROFEN DEGRADATION; AQUATIC ENVIRONMENT; CARASSIUS-AURATUS; TREATMENT PLANTS;

D O I：

10.1038/s41598-018-29524-1

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The efficiency of advanced oxidation processes (AOPs) for disposing of non-steroidal anti-inflammatory drugs (NSAIDs) has been widely studied, but the environmental fates and effects of the NSAIDs and their degradation products (DPs) are poorly understood. In this study, the efficiency of ultraviolet light/Na2S2O8 (UV/PS) in degrading three NSAIDs-diclofenac, naproxen, and ibuprofen-and the toxicity of their DPs on Cyprinus carpio (C. carpio) was investigated. Results showed that the three NSAIDs can be completely removed (removal rate > 99.9%) by UV/PS, while the mineralization rate of the NSAIDs was only 28%. When C. carpio were exposed to 0.1 mu M NSAIDs, 10 mu M persulfate (PS), and 0.1 mu M DPs of the NSAIDs for 96 h, respectively, the toxicity effects are as the NSAID DPs > PS > NSAIDs. Research results into the time-dependent effect of NSAID DPs on C. carpio demonstrated that obvious toxicity effects were observed in the first 48 hours, and the toxicity effects strengthened over time. NSAID DPs may have more severe toxicity effects than NSAIDs on C. carpio; therefore, the operating conditions of UV/PS must be optimized to eliminate the ecotoxicity of DPs.

引用

页数：11

共 69 条

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