TRITERPENE GLYCOSIDES FROM Astragalus AND THEIR GENINS. LXXXVII. CHEMICAL TRANSFORMATION OF CYCLOARTANES. IX. PARTIAL SYNTHESIS OF CYCLOASALGENIN

被引:5
|
作者
Isaev, I. M. [1 ]
Iskenderov, D. A. [1 ]
Isaev, M. I. [1 ]
机构
[1] Acad Sci Uzbek, S Yu Yunusov Inst Chem Plant Subst, Tashkent, Uzbekistan
关键词
Astragalus; Leguminosae; cycloartanes; cycloasalgenin; PMR; (13)C NMR; DEPT spectra;
D O I
10.1007/s10600-010-9629-y
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The natural cycloartane triterpenoid cycloasalgenin, which is 20R,24S-epoxycycloartan-3 beta,6 alpha,25-triol-16-one, was partially synthesized in three steps starting from cyclosiversigenin. In addition to the desired product, its 17-epimer was synthesized. The analogous 17-epimer was also prepared from cycloadsurgenin.
引用
收藏
页码:407 / 411
页数:5
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