Case report of a fatal rectal haemorrhage in a person with severe haemophilia A receiving emicizumab and high-dose bypassing agents in the HAVEN 1 study

被引:6
作者
Khoo, Liane [1 ]
Matthews, Stephen [1 ]
Kershaw, Geoffrey [1 ]
Pidcock, Michael [2 ]
Phipps, Alex [3 ]
Kiialainen, Anna [4 ]
Chang, Tiffany [5 ]
机构
[1] Royal Prince Alfred Hosp, Inst Haematol, Sydney, NSW 2050, Australia
[2] Canberra Hosp, ACT Pathol, Canberra, ACT, Australia
[3] F Hoffmann La Roche Ltd, Welwyn Garden City, Herts, England
[4] F Hoffmann La Roche Ltd, Basel, Switzerland
[5] Genentech Inc, San Francisco, CA 94080 USA
关键词
PROPHYLAXIS; INHIBITORS;
D O I
10.1111/hae.14110
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E340 / E343
页数:4
相关论文
共 10 条
[1]   Differential response to bypassing agents complicates treatment in patients with haemophilia and inhibitors [J].
Berntorp, E. .
HAEMOPHILIA, 2009, 15 (01) :3-10
[2]   Early long-term FEIBA prophylaxis in haemophilia A patients with inhibitor after failing immune tolerance induction: A prospective clinical case series [J].
Ettingshausen, C. Escuriola ;
Kreuz, W. .
HAEMOPHILIA, 2010, 16 (01) :90-100
[3]  
Genentech, 2018, HEMLIBRA EM KXWH INJ
[4]   A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model [J].
Kitazawa, Takehisa ;
Igawa, Tomoyuki ;
Sampei, Zenjiro ;
Muto, Atsushi ;
Kojima, Tetsuo ;
Soeda, Tetsuhiro ;
Yoshihashi, Kazutaka ;
Okuyama-Nishida, Yukiko ;
Saito, Hiroyuki ;
Tsunoda, Hiroyuki ;
Suzuki, Tsukasa ;
Adachi, Hideki ;
Miyazaki, Taro ;
Ishii, Shinya ;
Kamata-Sakurai, Mika ;
Iida, Takeo ;
Harada, Aya ;
Esaki, Keiko ;
Funaki, Miho ;
Moriyama, Chifumi ;
Tanaka, Eriko ;
Kikuchi, Yasufumi ;
Wakabayashi, Tetsuya ;
Wada, Manabu ;
Goto, Masaaki ;
Toyoda, Takeshi ;
Ueyama, Atsunori ;
Suzuki, Sachiyo ;
Haraya, Kenta ;
Tachibana, Tatsuhiko ;
Kawabe, Yoshiki ;
Shima, Midori ;
Yoshioka, Akira ;
Hattori, Kunihiro .
NATURE MEDICINE, 2012, 18 (10) :1570-U177
[5]   Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors [J].
Konkle, B. A. ;
Ebbesen, L. S. ;
Erhardtsen, E. ;
Bianco, R. P. ;
Lissitchkov, T. ;
Rusen, L. ;
Serban, M. A. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2007, 5 (09) :1904-1913
[6]   Anti-Inhibitor Coagulant Complex Prophylaxis in Hemophilia with Inhibitors [J].
Leissinger, Cindy ;
Gringeri, Alessandro ;
Antmen, Bulent ;
Berntorp, Erik ;
Biasoli, Chiara ;
Carpenter, Shannon ;
Cortesi, Paolo ;
Jo, Hyejin ;
Kavakli, Kaan ;
Lassila, Riitta ;
Morfini, Massimo ;
Negrier, Claude ;
Rocino, Angiola ;
Schramm, Wolfgang ;
Serban, Margit ;
Uscatescu, Marusia Valentina ;
Windyga, Jerzy ;
Zulfikar, Bulent ;
Mantovani, Lorenzo .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (18) :1684-1692
[7]   European Study on Orthopaedic Status of haemophilia patients with inhibitors [J].
Morfini, M. ;
Haya, S. ;
Tagariello, G. ;
Pollmann, H. ;
Quintana, M. ;
Siegmund, B. ;
Stieltjes, N. ;
Dolan, G. ;
Tusell, J. .
HAEMOPHILIA, 2007, 13 (05) :606-612
[8]   Emicizumab Prophylaxis in Hemophilia A with Inhibitors [J].
Oldenburg, Johannes ;
Mahlangu, Johnny N. ;
Kim, Benjamin ;
Schmitt, Christophe ;
Callaghan, Michael U. ;
Young, Guy ;
Santagostino, Elena ;
Kruse-Jarres, Rebecca ;
Negrier, Claude ;
Kessler, Craig ;
Valente, Nancy ;
Asikanius, Elina ;
Levy, Gallia G. ;
Windyga, Jerzy ;
Shima, Midori .
NEW ENGLAND JOURNAL OF MEDICINE, 2017, 377 (09) :809-818
[9]   Impact of inhibitors on hemophilia A mortality in the United States [J].
Walsh, Christopher E. ;
Soucie, J. Michael ;
Miller, Connie H. .
AMERICAN JOURNAL OF HEMATOLOGY, 2015, 90 (05) :400-405
[10]   Factor VIII inhibitors in hemophilia A: rationale and latest evidence [J].
Witmer, Char ;
Young, Guy .
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2013, 4 (01) :59-72