Short and long-term outcomes of the re-hepatectomies as part of multi-modal treatment of hepatic metastases from colo-rectal origin. Bi-institutional study

被引:0
作者
Nari, Gustavo [1 ]
Mariot, Daniela [1 ]
Gongora-Ortega, Javier [2 ]
Lopez-Ben, Santiago [3 ]
Albiol, Maite [3 ]
Figueras, Joan [3 ]
机构
[1] Hosp Transito Caceres Allende, Dept Surg, Cordoba, Argentina
[2] ISEA, Biostat Unit, Aguascalientes, Aguascalientes, Mexico
[3] Hosp Josep Trueta, Dept Surg, Hepatobiliopancreat Surg Unit, Girona, Spain
来源
CIRUGIA Y CIRUJANOS | 2018年 / 86卷 / 04期
关键词
Hepatic metastases; Colo-rectal; Repeated hepatectomy; Survival; Prognostic factors;
D O I
10.24875/CIRUE.M18000050
中图分类号
R61 [外科手术学];
学科分类号
摘要
Introduction: A high percentage of patients undergoing hepatectomy for metastatic colorectal liver disease will have a recurrence. Of these, some can be subject to a new resection. The usefulness of repeated hepatectomy remains controversial. The aim of this study is to evaluate the results of short and long-term outcomes in repeated hepatectomies. Methods: They were re-analyzed 68 repeated hepatectomies from two institutions. Demographics, characteristics of metastatic disease and hepatic resections were analyzed. Types of complications, morbidity and mortality were also analyzed as survival and disease-free time. Some of the factors of poor prognosis mentioned in the literature were evaluated. Results: The analysis of short-term data showed no statistically significant differences between patients with first and repeated hepatectomy, except the percentage of postoperative billery leakage (p = 0.001). The 1-year survival was similar while 3 and 5 years survival showed significant differences (p = 0.024 and 0.004, respectively). The factors of poor prognosis referred in the literature were not representative in this series. Conclusion: The short-term results of repeated hepatectomy are similar to those resoled once. Long term result are inferior to other published series.
引用
收藏
页码:306 / 313
页数:8
相关论文
共 39 条
[1]   Repeat hepatic resection for colorectal liver metastases [J].
Adair, R. A. ;
Young, A. L. ;
Cockbain, A. J. ;
Malde, D. ;
Prasad, K. R. ;
Lodge, J. P. A. ;
Toogood, G. J. .
BRITISH JOURNAL OF SURGERY, 2012, 99 (09) :1278-1283
[2]   Repeat hepatectomy for colorectal liver metastases [J].
Adam, R ;
Bismuth, H ;
Castaing, D ;
Waechter, F ;
Navarro, F ;
Abascal, A ;
Majno, P ;
Engerran, L .
ANNALS OF SURGERY, 1997, 225 (01) :51-60
[3]   The Oncosurgery Approach to Managing Liver Metastases from Colorectal Cancer: A Multidisciplinary International Consensus [J].
Adam, Rene ;
De Gramont, Aimery ;
Figueras, Joan ;
Guthrie, Ashley ;
Kokudo, Norihiro ;
Kunstlinger, Francis ;
Loyer, Evelyne ;
Poston, Graeme ;
Rougier, Philippe ;
Rubbia-Brandt, Laura ;
Sobrero, Alberto ;
Tabernero, Josep ;
Teh, Catherine ;
Van Cutsem, Eric .
ONCOLOGIST, 2012, 17 (10) :1225-1239
[4]   Hilar cholangiocarcinoma: The number of positive nodes and positive node/total node ratio is a significant prognostic factor for survival [J].
Adrian Nari, Gustavo ;
German Palacios, Oscar ;
Lopez-Ben, Santiago ;
Albiol, Maite ;
Falgueras, Laia ;
Castro-Gutierrez, Ernesto ;
Figueras, Joan .
CIRUGIA ESPANOLA, 2014, 92 (04) :247-253
[5]   Role of repeated hepatectomy in the multimodal treatment of hepatic colorectal metastases [J].
Ahmad, Aziz ;
Chen, Steven L. ;
Bilchik, Anton J. .
ARCHIVES OF SURGERY, 2007, 142 (06) :526-531
[6]   The "50-50 criteria" on postoperative day 5 - An accurate predictor of liver failure and death after hepatectomy [J].
Balzan, S ;
Belghiti, J ;
Farges, O ;
Ogata, S ;
Sauvanet, A ;
Delefosse, D ;
Durand, F .
ANNALS OF SURGERY, 2005, 242 (06) :824-829
[7]   SURGICAL ANATOMY AND ANATOMICAL SURGERY OF THE LIVER [J].
BISMUTH, H .
WORLD JOURNAL OF SURGERY, 1982, 6 (01) :3-9
[8]   Multi-modality treatment of colorectal liver metastases [J].
Cai, Guo-Xiang ;
Cai, San-Jun .
WORLD JOURNAL OF GASTROENTEROLOGY, 2012, 18 (01) :16-24
[9]  
Cunha AS, 2007, ARCH SURG-CHICAGO, V142, P1144
[10]   Repeat Curative Intent Liver Surgery is Safe and Effective for Recurrent Colorectal Liver Metastasis: Results from an International Multi-institutional Analysis [J].
de Jong, Mechteld C. ;
Mayo, Skye C. ;
Pulitano, Carlo ;
Lanella, Serena ;
Ribero, Dario ;
Strub, Jennifer ;
Hubert, Catherine ;
Gigot, Jean-Francois ;
Schulick, Richard D. ;
Choti, Michael A. ;
Aldrighetti, Luca ;
Mentha, Gilles ;
Capussotti, Lorenzo ;
Pawlik, Timothy M. .
JOURNAL OF GASTROINTESTINAL SURGERY, 2009, 13 (12) :2141-2150